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Biomedical subjects

V Neumann

Publications and source records attributed to V Neumann.

43 records · Page 3Linked to original sources

[Epidemiological and clinical problems in multiple sclerosis].

After a short discussion of the incidence rate and the distribution of multiple sclerosis in the world, some epidemiological problems are dealt with. Multiple sclerosis is a relatively frequent disease occurring mainly in zones of temperate climate, in highly civilised and technically advanced countries, and it is mainly found among the white (European) race. Clinically important appraisal criteria are pointed out. Retaining or regaining of efficiency and working capacity are regarded as simple assessment criteria of long-term therapeutic efforts.

Adult

[Surgical therapy of odontogenic maxillary sinusitis. Report on 397 cases].

Operative procedures were carried out on 410 maxillary sinuses in 397 patients. The most frequent indications for surgery were communication between the mouth and the atrium (55.4%) and cysts (24.2%). A Caldwell-Luc operation was carried out in 76.6% of the cases (radical operation). Vestibulum-cheek flaps were used to close the fistula in 97% of the cases. A follow-up examination of 220 patients showed that 10.2% complained of pain. The indications for surgery were limited to avoid this lasting damage.

Adolescent

CSF -- oligoclonal bands in multiple sclerosis.

The present paper is concerned with a correlation between clinical parameters of multiple sclerosis and different agar gel electrophoretical patterns in CSF. The agar gel electrophoresis represents clearly the most sensitive method for the demonstration of oligoclonal bands in CSF.

Adult

A multicentre pilot study of sulphasalazine in juvenile chronic arthritis.

In this multicentre pilot study of sulphasalazine in juvenile chronic arthritis, the mode of onset and course of the disease, and when available, the HLA status, was recorded on the entry form. After appropriate clinical and laboratory appraisal, sulphasalazine up to 40 mg/kg/day was given for one year with assessments at 0, 1, 3, 6, 9 and 12 months. Fifty-one patients enrolled, 8 of whom were withdrawn because of side effects. In the remainder by 12 months a good effect was noted in 12, 8 having pauci-articular onset disease commencing after the age of 9 years, of whom 6 carried HLA B27. It was relatively ineffective in the other subgroups. The frequency and severity of side effects was similar to that seen in adults. Further evaluation in controlled trials is required in older onset pauci-articular arthritis, taking due note of the patient's HLA status, and also in juvenile psoriatic arthritis and seropositive juvenile rheumatoid arthritis.

Adolescent