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Biomedical subjects

V N Nikitin

Publications and source records attributed to V N Nikitin.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Age-related peculiarities of acetylation of rat liver nuclear histones].

The intensity of acetylation of different histone fraction is found to change in postnatal ontogenesis of albino rats. The intensity of acetylation of lisine-rich histone (F1) was maximal in 3-and 12-month old animals. The label incorporation into F3 (arginine-rich) histones considerably decreased in the time interval between 1st and 3d months while its incorporation increased into F2 histones furing all the period of postnatal development studied.

Acetylation↗
PubMedDate not supplied

[Age-related characteristics of the effect of periodic low-calorie nutrition on lipid composition of the liver cells, small intestine, adipose tissue and blood serum in albino rats].

It is studied how long-term periodical calorie-insufficient and growth-restraining nutrition promoting appreciable life prolongation in the Wistar-line albino rats influences the lipid metabolism. It is shown that diet has an essential influence on the levels of phospholipids, cholesterol, neutral lipids, fatty acids in different tissue cells. The age specificity is observed in all the studied tissue cells. The lipid composition of cells in aged rats with prolonged life is similar to that of young animals of control group.

Adipose Tissue↗
PubMedDate not supplied

[Approaches to the experimental prolongation of life].

Modern approaches to lifespan prolongation of laboratory animals are considered. Calorie-deficient diet increasing lifespan, leads to essential hormonal shifts, to changes in the activity of genome, protein biosynthesis. These mechanisms determine lifespan prolongation.

Aging↗