Search PubMedSearch

Biomedical subjects

V N Lavrov

Publications and source records attributed to V N Lavrov.

14 recordsLinked to original sources

[Prosthesis in sequelae of tuberculosis of the femur head].

Endoprosthetic surgery on the head of the femur to correct aftereffects of tuberculous coxitis has been conducted in 23 patients. A combined preoperative preparation implying normalization of external respiration and cardiovascular function, x-ray examination of the proximal femur and cotyloid cavity specified indications for endoprosthetics, method of the pedicle fixation and the scope of the intervention. 6-month to 8-year outcomes are available. Overall functional results are satisfactory: all the patients but 2 (aged 64-66, underwent unipolar endoprosthetics) could walk without support.

Aged

[Use of biocompatible polymer implants in combination with extrafocal device fixation in the surgical treatment of spondylitis].

The author summarized the data on experimental application of biocompatible implants IIIIIM-1 covered with benemycin as a treatment modality in spondylitis. The polymer implanted into the disease focus is able to maintain high concentration of the drug for 60 days. The implants were inserted in 120 tuberculous and 27 nonspecific spondylitis patients. Surgical intervention performed in 147 patients comprising radical resection of the destruction focus and vertebral defect replacement with biocompatible implant in combination with extrafocal apparatus fixation decreased the operation trauma++, secured stability of the anterior and posterior parts of the operated spine and allowed early active rehabilitation of postoperative patients, 2-3 months after the surgery the author observed good spinal stabilization and definite signs of clavus formation in the resection zone.

Aged

[Primary disability in patients with tuberculous spondylitis and the ways for its decrease].

Causes responsible for invalidity were analysed in 167 patients with a circumscribed form of tuberculous spondylitis. The causes were divided into 4 groups: diagnostic errors; errors in treatment; prognostic errors (late indications to surgical treatment); organizational errors. Heightening of the quality of early diagnosis of tuberculous spondylitis at a primary application to a medical institution and timely high-quality specific therapy in the antituberculous institutions will contribute to an increase in treatment effectiveness and invalidity reduction.

Adult

[The surgical treatment of disseminated forms of tubercular spondylitis using Byzov's apparatus].

Analysis of treatment of 123 patients with disseminated forms of tuberculous spondylitis is presented. Among the patients 67 (54.4%) subjects were over 55 years of age. The main cause of disseminated spondylitis forms was ungroundlessly prolonged conservative treatment under bed regime. As a result, symptoms of low cardiac activity were seen in 79 (64.2%), lymphovenous stasis in 22 (17.8%) and osteoporotic signs in 38 (30.8%) patients. Complications and concurrent diseases in 41 (33.3%) of the cases prompted surgery from the posterior approach, in 82 (66.7%)--from the anterior approach with replacement of the defect by an autograft or biocompatible implant with extrafocal posterior fixation of the operated segments by Byzov's apparatus. The patients became active beginning on days 7-12 of postoperation, which promoted reparative process normalization in the operative area. The late therapeutic results were studied in 117 patients. Support capacity recovered in 99 patients and improved in 18. The method used is functionally justified, well tolerated by patients and highly effective in treating the abnormality.

Adult

[Extra-focal instrumental fixation of the spine in the surgical treatment of tuberculous spondylitis].

The complex procedure for treating tuberculous spondylitis involving a short-term (1-2 months) antibacterial therapy and early functional resection of the diseased vertebral bodies with defect replacement by an autograft and extra-focal fixation of the resected spinal portion by Byzov's apparatus applied in 492 patients proved to be highly efficacious. The reliable apparatus fixation of the spinal zone operated on allows early (on day 7) activation of patients which promotes functional normalization of organs and systems, activation of reparative processes, shortening of treatment duration and reduction of disabled cases. Clinical and X-ray findings show that a bone block formed 4-6 months after surgery and 67% of the patients finished their therapy during a year. Introduction of the procedure into the treatment of spinal injuries and diseases will be of the socioeconomical value.

Adolescent

[Surgical treatment of hematogenic spinal osteomyelitis using extra-focal instrumental fixation].

A total of 78 cases with acute hematogenic vertebral osteomyelitis are analyzed. Diagnostic errors at the prehospital and hospital stages are specified in 42 cases (53.8 percent), that resulted in late start of adequate treatment. Preoperative antibacterial therapy was carried out 1 to 1.5 months before surgery consisting in radical resection of the focus with replacement of the defect with autotransplant and extra-focal++ fixation with Byzov's apparatus. After surgery the patients started exercises on days 5-10. This treatment resulted in formation of osseous block at the site of vertebral body resection in 3-4 months in 30.8 percent of cases, in 5-6 months in 57.7 percent, and in 10-12 months in 11.5 percent of patients.

Acute Disease

[External instrumental fixation of the spine in the treatment of spinal diseases and injuries].

The authors analyze the results of treatment of 358 patients with specific and nonspecific spondylitis and with aftereffects of unstable fractures of the vertebrae proper, who have been operated on the spine destruction or instability area with the extrafocal fixation of the operated on segments by means of the Byzov apparatus. This method has yielded good clinical and functional results, effected the stability of the anterior and posterior portions of the operated on sites; it permits early (starting from the 5th-10th day postoperation) exercise of the patients, helps normal functioning of the body organs and systems, and activates the repair processes in the operated on sites. The incidence rate of the postoperative complications drops drastically, the patients rapidly recover their working abilities, and the invalidism is more rare.

Adolescent

[Development and use of antitubercular biocompatible implants for the treatment of tuberculous spondylitis].

The paper deals with the experimental and clinical study of a new implantable therapeutical means based on biocompatible implants containing the antituberculous agent benemycin. The developed implantant having 4 coatings releases within 10 days as high as 37% of the applied drug benemycin. Then within further 30-70 days, release of the drug is 0.7% a day. The parallel bacteriological studies with the operative material placed in agar made 30-60 days after surgery have indicated that growth retardment in rabbits is 17-30 mm, which corresponds to the levels of rifandin (0.125-1.0 microgram/g tissue. The developed implantant has been used in 130 cases of the surgical treatment of tuberculous spondylitis in order to replace a defect of the body of a vertebra and to make a depot for the antituberculous drug just in the focus. Formation of the pulley at the site of intervention was noted in 57 (43.8%) cases within 5 months and in 62 (47.7%) cases within 10 months. The developed implantant has no toxicity and produces no allergic reactions. The position results of the treatment allows it to be recommended for use in clinical practice.

Adult