The ointment containing pig leukocytic interferon had a pronounced therapeutic effect in herpetic affections of the face skin and genitalia. It prevented eruption, shortened the period of its healing and eliminated subjective sensations. The therapeutic effect was observed in 265 (87.7 per cent) out of 302 patients with recurring Herpes simplex treated with ointment.

Adult↗

PubMed1983

[Effectiveness of injectable human leukocyte interferon in recurrent genital herpes].

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Adult↗

PubMed1982

[Local immunity in patients with herpes genitalis (clinical and electron microscope study)].

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Female↗

PubMed1982

[Viremia in genital herpes].

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Adult↗

PubMed1982

[Cellular immunity mechanisms in genital herpes].

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Female↗

PubMed1982

[Allergic dermatitis].

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Dermatitis, Atopic↗

PubMed1981

[Trial of the safety, reactivity and therapeutic effectiveness of an ointment containing swine leukocytic interferon].

An ointment containing porcine leucocytic interferon (PLI) with the use of lanolin as the base and addition of human serum albumin for stabilization of the antiviral activity and Tris-or Hepes-buffer solutions for stabilization of the medium pH value was studied. The trials on volunteers with herpetic affections of the face and genitalia showed absolute safety of the drug, its areactivity and sufficiently high therapeutic efficacy as compared to an ointment containing human leucocytic interferon. The positive effect was observed in 52 out of 78 patients. On the basis of these data the PLI may be recommended for further clinical trials.

Animals↗

PubMed1981