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Biomedical subjects

V N Fedoseeva

Publications and source records attributed to V N Fedoseeva.

At least 19 recordsLinked to original sources
PubMed2006

[Risk factors of allergopathy].

This review contains a detailed description of factors which determine the allergic danger in a region, the sources of allergens entering the environment, and classification of allergens according to their origin and ecological significance. The authors draw attention to the existing criteria of allergopathic conditions, which may serve as an important diagnostic index when establishing sensitization and performing specific diagnostics of allergic diseases. The article covers a complex of laboratory diagnostic methods, directed towards timely detection of allergopathology and its prevention.

Environmental Pollutants↗
PubMed2003

IgE and IgG antibodies to Malassezia spp. yeast extract in patients with atopic dermatitis.

The presence of immunoglobulins to Malassezia spp. surface proteins in the sera from patients with atopic dermatitis and healthy subjects was studied. It was found that 28% of 25 examined patients with atopic dermatitis had IgE antibodies to Malassezia spp. surface protein preparation. All patients and 5 healthy subjects had IgG antibodies to this preparation. The presence and concentration of specific IgE antibodies in patients with atopic dermatitis correlated with reverse titers of IgG antibodies to this preparation (r=0.782). The medians of values reciprocal to IgG antibody titers in patients with atopic dermatitis with and without specific IgE antibodies to the preparation and in healthy subjects were 64, 1024, and 16, respectively. The preparation derived from Candida albicans (candidine) and previously derived preparation from Malassezia did not cross-react. According to immunoblotting data, the preparation contains allergens presented by proteins with molecular weights 15, 36, 52-56, and 78.4 kDa.

Adolescent↗
PubMed1982

[Properties of liposomal allergens of Neisseria perflava].

Experiments on guinea-pigs were made to study the anaphylactogenic properties of neisserial allergens incorporated into phospholipid vesicles (liposomes). The anaphylactogenic activity of the liposomal allergens was found to be reduced as shown by the general anaphylactic reaction (anaphylactic shock) seen in the guinea-pigs sensitized with neisserial allergens. The effect under consideration was coupled with intense allergen accumulation by lung tissues of the sensitized guinea-pigs. It is assumed that the reduced anaphylactogenic activity is caused by allergen isolation from lung tissues by phospholipid membranes.

Allergens↗