The dynamics of the multiplication of gonococci and the parameters of their growth have been studied in the process of batch cultivation in liquid culture media with different content of bovine blood serum. The protective and stimulating action of the serum on the growth of gonococci has been shown. The optimization of the process of cultivation has been carried out; as a result, the growth of test strains in a culture medium containing no serum has been achieved. Phasic changes in the ultrastructure of gonococci in the process of their cultivation in liquid media have been followed. 9- to 12-hour cultures of gonococci grown in liquid culture media have been found the most valuable and physiologically active.

Cell Division↗

PubMed1987

[Ultrastructural analysis of penicillinase-producing strains of Neisseria gonorrhoeae isolated from patients with a recurrence of the disease].

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Gonorrhea↗

PubMed1987

[Intradermal test with the gonococcal allergen as a screening test for gonorrhea].

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Allergens↗

PubMed1987

[Ways and prospects of producing gonococcal vaccine].

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Bacterial Vaccines↗

PubMed1987

[Comparative study of the passive hemagglutination test with diagnostic agents prepared from pathogenic and cultured Treponema pallidum from different forms of syphilis].

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Aged↗

PubMed1987

[Effectiveness of experimental 16-day accelerated methods of the treatment of early forms of syphilis].

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Animals↗

PubMed1987

[Results of molecular genetic studies of cultured and pathogenic strains of Treponema pallidum].

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DNA, Bacterial↗

PubMed1987

[Physicochemical and biological properties of an allergen from Trichomonas vaginalis].

The chemical and biological characterization of the preparation, found to be strictly specific, is presented. The allergen is nontoxic and has sensitizing properties. The active principle of the preparation is protein.

Allergens↗

PubMed1987

[A case of urethritis caused by meningococcus].

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Adult↗

PubMed1987

[Results of serologic reactions in patients with early forms of syphilis before and after treatment with doxycycline and placental extract].

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Doxycycline↗