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Biomedical subjects

V Morales

Publications and source records attributed to V Morales.

At least 55 records · Page 3Linked to original sources
PubMed1979

Antenatal intestinal perforation and meconium peritonitis associated with the neonatal small left colon syndrome.

Although NSLCS has been considered to have a benign course, we have described an infant who had intrauterine intestinal perforation and meconium peritonitis associated with the NSLCS. Infants of diabetic mothers who are stillborn or who develop abdominal distention shortly after delivery should be suspected of having this complication of NSLCS. This disorder must also be considered in the differential diagnosis of infants who present with meconium peritonitis.

Colonic Diseases↗
PubMed1975

Metabolic studies with 65Zn. X. Biosynthesis of alkaline phosphatase in cultures of Pseudomonas fluorescens.

Alkaline phosphatase from Pseudomonas fluorescens has been partially purified. Labelled 65ZnCl2 in the culture medium is incorporated in the most purified preparations. The enzyme shows a pH optimum of 7.2-7.5 and a Km value for p-nitrophenyl phosphate of 1 times 10(-4). Zinc ions at high concentration inhibit enzyme activity. The protective effect of Mg on the inactivation of alkaline phosphatase by heat is also reported.

Alkaline Phosphatase↗
PubMed1969

[Amniotic fluid].

Explore the source record for details and available documents.

Amniotic Fluid↗
PubMedDate not supplied

Chromatin structure and dynamics: functional implications.

In eucaryotes, DNA packaging into nucleosomes and its organization in a chromatin fiber generate constraints for all processes involving DNA, such as DNA-replication, -repair, -recombination, and -transcription. Transient changes in chromatin structure allow overcoming these constraints with different requirements in regions where processes described above are initiated. Mechanisms involved in chromatin dynamics are complex. Multiprotein complexes which can contain histone-acetyltransferase, -deacetylase, -methyltransferase or -kinase activities are targeted by regulatory factors to precise regions of the genome. These enzymes have been shown to modify histone-tails within specific nucleosomes. Post-translational modifications of histone-tails constitute a code that is thought to contribute to the nucleosome or to the chromatin fiber remodeling, either directly, or through the recruitment of other proteins. Other multiprotein complexes, such as ATP-dependent remodeling complexes, play an essential role in chromatin fiber dynamics allowing nucleosome sliding and redistribution on the DNA. We will focus here on the chromatin structure and its consequences for DNA damaging, replication, repair, and transcription and we will discuss the mechanisms of chromatin remodeling.

Acetyltransferases↗
PubMedDate not supplied

Innovative programs for children and adolescents with spinal cord injury.

A few innovative programs have enabled children with SCI to surpass traditional levels of independence defined solely on preservation of motor function. Implementation of unique upper extremity and bladder surgical programs has provided children with tetraplegia the ability to manipulate objects without equipment and to independently empty their bladder, respectively. Innovative surgical programs have also restored privacy, dignity, and spontaneity. These are important gains previously unachievable by young persons with tetraplegia. Functional electrical stimulation has advanced children's abilities in upright mobility and has made significant impact on their quality of life by restoring hand and bladder capacities. Nurses play a leadership role in the delivery and integration of these dynamic programs.

Adolescent↗