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Biomedical subjects

V Metz

Publications and source records attributed to V Metz.

At least 37 records · Page 2Linked to original sources

Tumor vascularization: assessment with duplex sonography.

In this prospective study, the authors examined 123 patients with benign or malignant neoplasms (breast cancer, n = 44; liver neoplasms, n = 43; and tumors affecting other organs, n = 36) to establish general criteria for evaluation of neoplastic lesions by means of duplex sonography. The frequency shifts determined by means of different Doppler frequencies (2.31 or 3.75 MHz) were converted into flow velocities. Only the highest systolic peak flow velocity obtained from a lesion was used for statistical evaluation. Receiver operating characteristic curves showed that a flow velocity of 0.4 m/sec is the optimal threshold value with which to differentiate benign from malignant tumors. The data obtained in all lesions indicated that only positive findings are potentially reliable. It is concluded that negative results of sonography should not be used to diagnose the presence of a benign lesion. The resistive index of the tumors was of negligible importance.

Blood Flow Velocity↗

[Sonography of the skeletal muscles using high-frequency ultrasound probes].

8 musculi graciles of human cadavers were examined sonographically by means of high-frequency ultrasound probes (10 MHz) to evaluate the echo texture of skeletal muscles. It could be shown that the smallest structures of skeletal muscles that may be differentiated sonographically are the primary bundles. In addition, 100 patients with clinically suspected muscular trauma and 8 patients with neuromuscular diseases were examined via high-frequency ultrasound probes (10 or 7.5 MHz). The typical signs of muscle tears and neuromuscular diseases in relation to normal sonomorphology are discussed. The special value of the method in these indications is emphasised.

Humans↗

[CT and MRT in mediastinal and hilar space-occupying lesions].

Thirty-eight patients with mediastinal and/or hilar masses were imaged by computed tomography (CT) and magnetic resonance imaging (MRI). Results were analyzed retrospectively regarding the ability to demonstrate the masses, their number, size, definition, location and tissue characteristics. CT and MRI showed equivalent results in 32 cases; additional information was obtained in two patients by CT, in four patients by MRI. In view of the specific advantages and limitations of both CT and MRI we believed that in patients with mediastinal and/or hilar masses, contrast enhanced CT remains the procedure of choice after performing plain chest radiographs; in certain cases MRI will prove useful for further evaluation.

Adolescent↗

[Excretory urography: comparison of the ionic contrast medium amidotrezoic acid with the non-ionic contrast medium iohexol].

The contrast media diatrizoic acid and iohexol were compared in a randomized double-blind study on the basis of 100 excretory urograms. It was found that side effects are less frequent under the non ionic contrast medium than under the ionic agent, the difference being statistically significant at the level alpha = 0.05. No statistically significant difference was recognizable concerning the overall quality of the urograms.

Clinical Trials as Topic↗

[Diagnosis of liver trauma: ultrasound versus computed tomography].

This study used 14 of our own patients and a review of the literature in order to determine the value of CT and sonography for investigating injuries to the liver. It appears that CT, with a sensitivity of 0.93, has a somewhat higher accuracy than sonography, which has a sensitivity of 0.83. We were also able to observe typical changes in the appearances, depending on the interval since the injury. Fresh injuries appeared as isodense or mildly hypodense areas, together with variable hyperdense portions on CT. Subsequently these areas become increasingly hypodense and may evolve into cystic lesions. Sonographically, recent injuries of the liver show echo-rich, non-homogeneous lesions which may contain smaller echo-free portions. Older lesions become increasingly devoid of echoes and become increasingly demarcated from normal liver parenchyma.

Evaluation Studies as Topic↗

[Small parietal thrombi in artificial bypass grafts].

During the last five years, 51 femoro-popliteal polytetrafluoroethylene grafts were implanted in patients in the Second Surgical University Clinic, Vienna. In four of these patients an angiogram performed shortly after operation showed numerous small parietal thrombi on the artificial graft, a review of the literature has not shown any similar reports. The clinical importance and consequences of this observation are discussed.

Aged↗

[A modified laser system for laser angioplasty using a sapphire tip].

This study deals with 26 patients on whom successful laser angioplasty of peripheral vascular occlusions had been carried out, using an Nd-YAG high energy laser system (100 watts) with a sapphire point. The technical requirements are presented and the primary success and complication rates in our material are discussed.

Angioplasty, Balloon↗

The effect of reserpine and guanethidine on carbohydrate metabolism in ischaemic rat myocardium.

We have investigated the role of endogenous catecholamines in myocardial carbohydrate metabolism in isolated, perfused rat hearts after left coronary artery occlusion for 30 min. A significant decrease in ATP and glycogen, and an increase in glucose-6-phosphate (G-6-P) content in the ischaemic myocardium was obtained. After depletion of the cardiac noradrenaline stores by reserpine or guanethidine pretreatment the increase in the G-6-P levels was very markedly enhanced, and the myocardial glycogen content of non-ischaemic control hearts was significantly increased by reserpine. However, the amount of glycogen broken down during the ischaemia in pretreated animals was similar to that in the ischaemic myocardium from control animals, and the decrease in the myocardial ATP was not altered by reserpine or guanethidine. Thus the well known release of noradrenaline during myocardial ischaemia is not an essential prerequisite for the activation of the ischaemic breakdown of glycogen. Rather, it is of importance for later steps in anaerobic carbohydrate metabolism, probably for the activation of phosphofructokinase, as suggested by the large ischaemic accumulation of G-6-P in noradrenaline depleted hearts.

Adenosine Triphosphate↗

[Hemodynamic and clinical studies following injury of the arteries of the forearm].

Forearm arterial injury usually does not lead to acute ischemia, but a functional deficit may develop. We tried to evaluate the need for two patent forearm arteries using rheological, Doppler sonographical and clinical parameters. Twenty-seven patients were examined after arterial and/or nerve injury in the forearm as well as six patients in whom a forearm flap was harvested. In seventeen patients both arteries were patent after primary reconstruction. Nine patients showed only one patent artery, while in the six patients with a forearm flap the radial artery was reconstructed in only one case. We found a decreased skin temperature in cases with artery and nerve injury. If both structures were reconstructed, the difference was not significant. The pressure of the finger collateral arteries and of the forearm arteries as well as the rheological investigation did not show any difference. The two-point discrimination, reflecting the nerve regeneration, was not affected, if one or two arteries had been reconstructed. Pain following exercise rarely occurred if both arteries of the forearm were patent. Because of the positive effect on skin temperature and of the reduced pain following exercise, reconstruction of both forearm arteries should be considered. Furthermore, the possibility of a subsequent arterial injury has to be taken into account.

Adolescent↗

[Perforation of the right ventricle during pulmonary angiography: possible causes and their prevention].

This is a report on a perforation of the myocardium during pulmonary angiography. The choice of the catheter is very important for the occurrence of such complications. We used a Cook 7 French polyethylene multipurpose catheter, which did not guarantee sufficient stabilisation due to its small number of side holes during injection of contrast medium. On the other hand the straight top of the catheter promoted its penetration into the myocardium. To avoid such often lethal complications, catheters with pigtail configuration should be used.

Angiography↗

[Color-coded Doppler sonography of the pelvis-leg arteries: an appraisal of the value of that method in comparison with angiography].

The aim of this study was to determine the accuracy of colour-coded Doppler sonography (CDS) and its advantages as compared with angiography and pulsed Doppler sonography. For this purpose, the arteries in the pelvis, thigh and knee of 42 patients were examined by CDS, the gold standard being angiography. In ten patients, pulsed Doppler sonography was performed as well and the length of the examination compared with that of CDS. It was shown that CDS is valuable in the investigation of peripheral vessels and that it can replace angiography after femoro-popliteal bypass operations or PTA. Compared with pulsed Doppler sonography, CDS has the advantage of being much quicker.

Angiography↗

[Arteriovenous fistulas of the lung--their clinical aspects and radiologic images].

Based on the data of 15 patients the typical radiological signs of pulmonary arteriovenous fistulas, their differential diagnostic implications, clinical signs and symptoms and management are reviewed. In addition, lung function parameters of 9 patients are presented. The critical role of pulmonary angiography and sequential dynamic CT for the diagnosis is stressed, particularly in those cases in which conventional chest radiographs and tomographies fail to show characteristics abnormalities. Since pulmonary arteriovenous fistulas tend to increase in size and cause complications, they should be subjected to intermediate treatment, even if they are of no haemodynamic relevance.

Adolescent↗

Open meniscal repair: clinical and magnetic resonance imaging findings after twelve years.

The purpose of this study was to document the longterm clinical, radiographic, and magnetic resonance imaging results after open meniscal repair. Twenty-two patients, with 23 open meniscal repairs, were evaluated after a mean follow-up of 12.9 years using patient history, physical examination, KT-1000 arthrometer testing, the "Orthopaedische Arbeitsgemeinschaft Knie" knee evaluation scheme, Tegner activity score, weightbearing radiographs, and magnetic resonance imaging. Two of the 22 patients had retears and both occurred in unstable knees. Radiographs revealed no degenerative changes in 17 of the 23 compartments. Grade III and IV signal alterations were present on magnetic resonance imaging scans in more than 50% of the repaired menisci. We concluded that the longterm survival rate of repaired menisci was 91%, and that magnetic resonance imaging is unsuitable for diagnosis of the healing process of a repaired meniscus.

Adult↗