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Biomedical subjects

V Masini

Publications and source records attributed to V Masini.

At least 73 records · Page 4Linked to original sources
PubMed1977

[General anesthesia in patients with intraventricular conduction abnormalities (author's transl)].

This study was undertaken to assess the risk of developing complete heart block during general anesthesia in patients with bundle branch block. His bundle electrograms were recorded during sinus rhythm and after atrail pacing in 11 patients (5 LBBB, 2 RBBB, 3 RBBB and LAH, 1 RBBB and LBH) before and after administration of Pentothal 0.20 g e.v., Succinylcholine 1 mg/kg e.v., and breathing of fluothane 1%or Ethrane. Minimal effects on sinus functions and A-V node conduction was observed during anesthesia; Fluothane only increased slightly AH intervals (+11%). Both Fluothane and Ethrane effects on HV conduction was insignificant. In 9 patients HV intervals increased of 5% after Succinylcholine; 2 patients developed a complete heart block distal to his after the drug. Possible causes of the complete heart block are discussed and a direct effect of Succinylcholine is hypothesized.

Anesthesia, General↗
PubMed1976

[Natural history of unstable angina. Observations on 157 cases (author's transl)].

157 cases affected with "unstable angina" and hospitalized were observed over a period of from 8 to 24 months (average observation time: 16 1/2 months). The patients were treated with: nitroderivates, beta blocking drugs (when not contra-indicated); treatment of side affects (hypertension; arrhythmias, decompensation, associated pathology, correction of risk factors of coronary heart disease). 9 cases were lost and 148 were studied for the course of the illness. 10.6% died from cardiopathy (2.8% through sudden death; 7.4% from myocardial infarction); there was a 12.1% total incidence of myocardial infarction; 50% of the cases were alive but with sumptoms of stabilized angina, whilst 32.4% were completely asymptomatic. Coronographic alterations and myocardial contractility negatively affect the course of the illness. Negative effects (disease or infarction) were not checked in the cases of stenosis of only one coronary branch. In the casuistry, there were no negative effects in patients with stenosis of one coronary branch, and in cases of two or more branches, negative effects were 28%. 41% of patients with alterations of ventrical contractility gave negative results. An asymptomatic course of the illness was checked more frequently in the intermediate stages than in angina cases.

Angina Pectoris↗
PubMed1976

[On the method for determination of sinus node recovery time (author's transl)].

On the basis of personal experience of 22 patients, 11 with sick sinus node syndrome (SSNS) and 11 without, it was concluded that the seat and length of atrial stimulation has little importance for the determination of recovery time for corrected sinus node (RTCSN). The frequency of optimal stimulation seems to be 110 impulses per minute for 2 minutes, by which it generally reaches the maximum value of RTCSN. Using this method, the falsely normal RTCSN in SSNS subjects can be verified; in these cases the test should be repeated within a larger frequency scope.

Arrhythmia, Sinus↗
PubMed1976

[The values and limitations of recovery time in sick sinus syndrome (author's transl)].

143 patients were examined for SNRT and thus divided: 1st group: 39 patients with indisputable clinical signs of MNS (bradycardia-tachycardia, synocopes); 2nd group: 18 patients with constant sinusal bradycardia, but without arrhythmias; 3rd group: 86 patients without any clinical signs of sisusal automatism deficit. The average SNRT results were: 2346 plus or minus 1404 msec in the 1st group; 1337 plus or minus 181 msec in the 2nd group and 1021 plus or minus 216 msec in the 3rd. Corrected SNRT gave an average result of 1315 plus or minus 1300 msec in the 1st group; 329 plus or minus 229 msec in the 2nd and 234 plus or minus 133msec in the 3rd group. The values between the average and standard deviation...

Adult↗
PubMed1976

[Systolic time intervals in obstructive hypertrophic cardiomyopathy. The effects of adrenergic beta-stimulation and beta-blockade in 38 cases (author's transl)].

The authors report on the behaviour of systolic time intervals, studied with a noninvasive poligraphic technique, under normal conditions, after adrenergic beta stimuls (orciprenaline) and successive beta blocker (pindolole) in 38 patients with obstructive cardiomyopathy. Under normal conditions, the authors observed a marked dispersion of PEP and TEVS data, which have, however, average normal values. The IPEP was reduced in 29% of cases, was normal in 47.3% and raised in 23.7%; the ITEVS was reduced in 55.2% of cases, was normal in 21.1%, raised in 23.7%; the PEP/TEVS was reduced in 23.7%, normal in 31.6% and raised in 44.7%. The beta stimulation demonstrated a number of behaviour patterns: the most frequent cause was a reduction of PEP in the cases where it had been raised or where it had remained within normal limits, an increase of TEVS in the cases where it had been diminished or normal, a reduction of the PEP/TEVS correlation where these values were increased or normal. The beta blocker, followed by beta stimulus, brought on variations opposite from those of the beta stimulation. Thus, one can consider the hypothesis that the possible behaviour patterns and combination of PEP and TEVS result from different anatomical and functional expressions that can become obstructive cardiomyopathy, according to the seriousness of the obstruction, the ventricular compliance and the contractility.

Adult↗
PubMed1976

[Familial sick sinus syndrome. Observations on three cases studied (author's transl)].

Three siblings with sick sinus syndrome (SSS) are described. In each case, electrocardiogram, Hisian electrogram and sinus node recovery time were recorded, both in basic conditions and under the effect of drugs. In two cases a permanent pacemaker uas applied. The clinical and instrumental investigations were extended to 24 out of 33 cases included in the complete genealogical tree; three cases with arrhythmias were identified (atrial and ventricular extrasystoles and atrial fibrillation). From a genetic point of view, the SSS seemed to segregate a dominant autosomic character with a lower frequency of the disease in the descendants then expected, which is probably due to their low age.

Adult↗
PubMed1976

[Hemochromatosic cardiomyopathy. Report of a case with registration of his bundle potentials and hemodynamic examination (author's transl)].

A case of idiopathic haemochromatosis in a young adult aged 23, with pre-eminent cardiac symptoms is described. The cardiac symptoms consisted of heart failure and various types of arrhythmias (atrial and ventricular tachycardia, AV block). The haemodynamic studies revealed a biventricular diastolic hypertension; the cineangiocardiography showed a diffuse hypokinesis of the left ventricle and mitral regurgitation.

Adult↗
PubMed1976

[Coronarographic and ventriculographic aspects of 76 cases of unstable angina (authors transl)].

-- Coronarographic and ventriculographic aspects of 76 patients with unstable angina were analyzed. 8 cases (10%) had normal coronary arteries, 9 (11.8%) had slight stenotic lesions (less than 50%), 59 (77.6%) had serious stenosis. The stenosis concerned only one principal branch in 22 patients (37.2%), 2 branches in 24 (40%), 3 branches in 13 (22%). In 77-79% of cases, ventricular contractility was normal. A collateral circulation was found in 58% of cases, but no link was discovered between the coronaric lesions and the clinical type of angina. The course of the illness was studied during the hospitalization and post-hospitalization period for an average observation time of 14 months (55 cases). The course of illness type depends on the number of affected branches and the myocardial contractility. In 25% of the patients with lesions in 3 branches there was an unfavourable course of illness (either infarction or death), whilst where there were lesions in one or two branches, negative results were 11% and 15% respectively. Patients with normal coronary arteries or slight stenosis had no unfavourable course of illness. In 37% of patients with altered contractility, an unfavourable course of illness was found, as against 27% with normal contractility. The presence of collateral circulation doesn't seem to influence the course the illness takes. A coronarographic examination seems to be an essential elelment in deciding on the prognosis of unstable angina.

Angina Pectoris↗