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Biomedical subjects

V M ZHDANOV

Publications and source records attributed to V M ZHDANOV.

At least 37 records · Page 2Linked to original sources
PubMed1961

Inhibition of virus and T-haemagglutination by typhoid fever Vi-antigen.

This paper reports on tests of the effect of polysaccharide-lipid antigens of enteric bacteria and Rickettisa prowazekii antigen on virus and T-haemagglutination. It is shown that treatment of erythrocytes with typhoid Vi-antigen greatly reduces their agglutinability by myxoviruses or the Stewart-Eddy polyoma virus.Erythrocytes treated with typhoid antigen retained their capacity to adsorb and elute myxoviruses, although to a somewhat lesser degree than normal erythrocytes, and such treatment did not affect adsorption of the SE polyoma virus. The typhoid antigen does not fix or destroy the virus receptor of the erythrocyte.Adsorption of the typhoid antigen prevents T-agglutination of erythrocytes which have first been treated with receptor-destroying enzyme. On the surface of RDE-treated erythrocytes the typhoid antigen is fixed outside the T-antigen loci and does not block unmasked T-antigen. The general conclusion is that, in the systems reviewed, the Vi-antigen is able to increase the resistance of erythrocytes to agglutination.

Antigens, Bacterial↗
PubMed1961

Use of the haemagglutination-inhibition test in the study of museum strains of neuroviruses.

Haemagglutinating antigens for various strains of tick-borne and Japanese B encephalitis viruses and for certain mutants of the virus of American equine encephalomyelitis have been prepared at the D. I. Ivanovski Institute of Virology of the USSR Academy of Medical Sciences, Moscow, and used in cross haemagglutination-inhibition tests with the corresponding immune sera. The results of these experiments suggest that the haemagglutination-inhibition test using goose red cells constitutes a simple, rapid and accurate method for the serological diagnosis of diseases caused by the neuroviruses mentioned above and for the identification of isolated strains of these viruses, and would be of considerable value in epidemiological surveys.

Animals↗