[Acute and chronic bronchopulmonal diseases in patients with chronic HBV infection].
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Acute Disease↗
Biomedical subjects
V M Provotorov
Publications and source records attributed to V M Provotorov.
[Characterization of arrhythmia in pulmonary hypertension in patients with bronchial obstructive diseases].
To study the pattern and incidence of arrhythmias in relation to the mean pulmonary trunk pressure (MPTP), 24-hour SCG monitoring and Doppler pulse EchoCG were performed in 32 patients with chronic obstructive lung disease and in 13 patients with bronchial asthma. The summarized results of 24-hour ECG suggest that the number and grades of arrhythmias increase when MPTP becomes more than 13 mm Hg. There is a highly significant mean force correlation between MPTP and complicated cardiac arrhythmias (paroxysmal supraventricular tachycardia, coupled ventricular extrasystoles, and unsteady ventricular tachycardia). A more than 13 mm increase in MPTP may be a predictor for the assessment of a risk of the existence of complicated cardiac arrhythmias on an exacerbation of bronchial obstructive lung diseases.
Adult↗
[Clinical characteristics of hypertensive disease in patients with alexithymia].
AIM: To study hemodynamics and metabolism in patients with hypertensive disease and various severity of alexithymia. MATERIAL AND METHODS: Psychological testing was included into complex examination of 202 patients with stage II hypertensive disease. RESULTS: Patients with alexithymia had longer duration of hypertensive load, higher frequency of target organs damage, intensified processes of lipid peroxidation and depressed activity of antioxidant defense, derangements of lipid metabolism. Twenty four hour blood pressure index characterizing day-night pressure gradient depended on the psychological status of patients. Nocturnal hypertension or insufficient nocturnal lowering of blood pressure were more frequent in patients with alexithymia. CONCLUSION: The presence of alexithymic personality traits was associated with more severe clinical presentation of hypertensive disease.
Affective Symptoms↗
[Clinical-diagnostic significance of the study of medium mass molecular spectrum in patients with bronchial asthma combined with diabetes mellitus].
Bronchial asthma (BA) and diabetes mellitus (DM) aggravate each other. Endogenic intoxication (EI) takes place both in BA and DM. Therefore, patients with BA and DM combination have chronic EI. A severe course of BA and DM can be judged not only clinically but also by spectrogram of medium mass molecules (MMM). BA patients have two peaks, maximal of them reaches 0.20 units of total area, total area being 0.4822 +/- 0.0186. In combination of BA with DM there are five peaks, on the average, maximal one reaches 0.30 uta and total area is 0.9207 +/- 0.029. Plasmapheresis, adjuvant to basic therapy, improves clinical course, MMM spectrogram exhibits less number of the peaks, their height and total area.
Adult↗
[Quality of life of patients in post-myocardial infarct period].
Relationships between the quality of life (QL), psychological status and severity of cardiovascular impairment were studied in 96 males after anterior large-focal myocardial infarction. A positive moderately strong correlation was found between GL and left ventricular ejection fraction. Alexitimia affects the response of the patients to basic limitations diminishing QL. Alexitimia patients have harmful behavioral habits (smoking, alcohol abuse) two times more frequently than patients free of alexitimia. Adequate methods of alexitimia psychotherapeutic correction should be introduced.
Adult↗
[The characteristics of the clinical manifestations and treatment of chronic obstructive bronchitis in patients with hepatobiliary system diseases and pseudoallergy].
Routine clinical, laboratory, instrumental and immunological examinations in 105 patients have established that hepatobiliary disorders occur 2.2 times more frequently in patients with chronic obstructive bronchitis (COB) and pseudoallergy than in those without pseudoallergy. To correct negative effects of pseudoallergy, conventional therapy was combined with enterosorbent polyphepan, spasmolytic nospa and cholagogic allochol used alone or in different combinations. The highest benefit for COB patients was achieved in using combination of polyphepan + nospa + allochol.
Adult↗
[The characteristics of the clinical course and treatment of chronic obstructive lung diseases against a background of lymphoproliferative diseases].
The authors studied expectoration, cough clearance and immunity in 48 patients with exacerbation of chronic obstructive pulmonary affections (COPA) associated with lymphoproliferative diseases (chronic lymphoid leukemia, lymphocytic lymphoma, myeloma) versus 16 control patients suffering from COPA alone. patients of the test group received cytostatics and steroids according to standard schemes. They are shown to develop aggravation of immune defects with emergence of persistent secondary immunodeficiency, more marked disturbance of tracheobronchial clearance with more frequent occurrence of persistent ciliary dyskinesia. This resulted in slower relief of clinical symptoms, more severe course dictating the necessity of longer treatment, the addition of immunocorrectors, antibacterial drugs without immunosuppressive action.
Adult↗
[Alexithymia in personal characteristics of patients with coronary heart diseases].
Psychological status was assessed in 120 patients with coronary heart disease (CHD) according to MMPI, Toronto alexithymic scale. Alexithymia was diagnosed in 49.1% of the examinees. They were characterized by difficulties in definition of their feelings, absence of dreams and fantasies, introversion, inclination to depressive response to stress, hypochondria eventuating in senesthopathy. The above psychological and pathopsychological traits in CHD patients require psychotherapeutic and chemotherapeutic correction in order to enhance efficacy of the treatment.
Adult↗
[Clinical effectiveness of enterosorbents in patients with chronic bronchitis and gestational toxicosis].
The authors studied efficacy of enterosorption with activated coal KM in patients with exacerbation of chronic bronchitis and gestosis. The trend in clinical and laboratory characteristics of the exacerbation and gestosis, external respiration, cellular and humoral immunity gives grounds for validity of using enterosorbents in patients with chronic bronchitis and late gestosis.
Acute Disease↗
[A comparative assessment of the clinical efficacy of standard and low-volume plasmapheresis in treating patients with bronchial asthma and chronic bronchitis].
21 patients with bronchial asthma and chronic obstructive bronchitis resistant to standard therapy have been exposed to discrete plasmapheresis. Changes in the bronchial tree inflammation measured by fibre bronchoscopy and activity of neuron-specific enolase (NSE) in bronchial wash-offs made it clear that low-volume plasmapheresis is not inferior in efficacy to the standard method. The trend in the fall of NSE activity as a marker of diffuse neuroendocrine system objectively reflects attenuating inflammation in bronchial mucosa in response to treatment of chronic obstructive diseases of the lungs using different techniques of plasmapheresis.
Adult↗
[Effects of different methods of drug administration on clinico-immunological indices and expectoration in patients with nonspecific lung diseases].
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Administration, Inhalation↗
[The correction of the imbalance in the proteinase-inhibitor system of patients with protracted pneumonia with the enterosorbent polifepan].
The evidence obtained by the authors indicates that enterosorbent polyphepan corrects unbalance in the proteinase-inhibitory system of bronchial lavage from patients with lingering pneumonia and endobronchitis. Clinical symptoms improved also. A long-term (18 days) intermittent course (0.3 g/kg 4 days with 3-day intervals) is tolerated satisfactorily, produces no side effects (no colon dysfunction), retains normal hemoglobin values, total protein, enhances antiproteinase activity. As a result of the treatment hospital stay for the above patients reduced noticeably.
Adolescent↗
[The comparative efficacy of treating patients with chronic bronchitis and late pregnancy toxicosis by using different enterosorbents].
Enterosorbents Polysorb MP and Polyfepan were tried in patients with chronic bronchitis in the stage of aggravation and with late gestosis. The trends in clinical and laboratory indices, in external respiration, cellular and humoral immunity, in the content of middle-weight molecules in relevant patients undergoing enterosorption with the above sorbents against the controls were more favourable. This supports validity of enterosorption in patients with chronic bronchitis and late gestosis.
Bronchitis↗
[Diagnosis of chronic obstructive bronchitis].
Cough and mucociliary clearances were investigated in patients with chronic obstructive bronchitis, chronic bronchitis, chronic nonobstructive bronchitis by ciliary activity of the ciliated epithelium and cough intensity according to the formulas, using inulin and tussographic techniques of expectoration testing. The findings above were compared to clinical manifestations of bronchitis, x-ray pictures, bronchial mucosa bronchoscopy and cytology, examination of external respiration. The analysis of the data obtained provided the conclusion that early diagnosis of chronic obstructive bronchitis is valid in ciliary activity of the ciliated epithelium equal or surpassing 1 and cough intensity under 35%.
Adolescent↗
[The clinico-diagnostic significance of qualitative cough indices in nonspecific lung diseases].
It is proposed to make a qualitative analysis of one of the most frequent bronchopulmonary symptoms--cough. This involves dynamic tussographic evaluation of the cough and expectoration in the original inulin test. The analysis covered such cough characteristics as resistance, efficacy, intensity, volleys assessed in patients with lung cancer, chronic bronchitis, tracheobronchial dyskinesia. Typical changes in the above indices observed in each of the patient groups have been defined which are essential for diagnosis and differential diagnosis.
Bronchitis↗
[The immediate and late results of treating patients with nonspecific lung diseases by using the local administration of kontrikal and antibiotics].
An analysis was made of the short- and long-term (1.5-2 years) results of the treatment of 75 patients with acute abscess and 101 with lingering pneumonia using different routes of administration of proteinase inhibitors and antibiotics. The high efficacy was demonstrated of the local intrapulmonary and endobronchial administration of the proteinase inhibitor contrykal and antibiotics. The treatment method suggested was found to compare favourably with the common route of the drug administration. The treatment is well tolerated and promotes the shortening of the times of the patients' stay in the hospital, reduces the number of complications and residual phenomena, prevents the disease relapses and their transformation to chronic nonspecific pulmonary diseases. The clinical recovery of the patients with acute lung abscess was reached in 91.4% of cases whereas in the reference group, only in 66.7%. In the patients with lingering pneumonia, the recovery was noted in 85.4%, in the reference group, in 27.5% of cases.
Acute Disease↗
[The clinical efficacy of treating patients with acute pneumonias by using drug and quantum correction of the lipid peroxidation-antioxidant system].
The authors describe the status of lipid peroxidation (diene conjugates and malonic dialdehyde) and the endogenous antioxidant enzyme superoxide dismutase in the course of the treatment of patients with acute focal pneumonia by means of the use of transthoracic intrapulmonary injections of unithiol and autologous ultraviolet blood radiation (AUVBR). Three groups of patients were entered into the study. The first group included 64 patients who were given transthoracic intrapulmonary injections of unithiol, the second group 58 patients who received 5-7 sessions of AUVBR, in the third group, 52 patients were given transthoracic intrapulmonary injections of unithiol coupled with 3-5 sessions of AUVBR. The control group was made up of 40 patients given intravenous unithiol injections in routine therapeutic doses. The results of the treatment evidence that combined correction of lipid peroxidation carried out in the third group patients was most effective. As regards the times, the positive dynamics of lipid peroxidation and superoxide dismutase activity correlated with the clinical, biochemical and x-ray improvement. Therefore the method of correction in question is a pathogenetically based approach, permitting one to enhance the clinical efficacy of the treatment of patients suffering from acute focal pneumonias and to reduce the times of their stay in the hospital by 5-7 days, on the average.
Acute Disease↗