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Biomedical subjects

V Levy

Publications and source records attributed to V Levy.

46 records · Page 3Linked to original sources

A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule.

A monoclonal antibody, 1B3.1, was raised against a cloned IL-2-dependent T cell line that expresses the T gamma delta T cell receptor. MoAb 1B3.1 reacted with long-term cultured T cell lines of both T gamma delta and T alpha beta lineage, and with in vivo-stimulated T cells, derived from synovial fluid, but not with resting or short-term activated T cells, B cells, or macrophages. Immunoprecipitation of the 1B3.1 target antigens showed that 1B3.1 recognizes a 200/110 kDa molecule that is identical to the VLA-1 heterodimer precipitated by MoAb TS2/7. 1B3.1, however, binds to an epitope of VLA-1 that is distinct from the TS2/7 binding site. This new MoAb could be useful in further studies of the functions of VLA-1, and of the cells that express this molecule.

Antibodies, Monoclonal↗

Survival time in gunshot and stab wound victims.

Forensic pathologists are often asked to estimate postinjury survival time and to render an opinion on the probable extent of physical activity following fatal injury. To study this question, the case files of the Dade County Medical Examiner's Office were reviewed. The year 1983 was chosen arbitrarily for this study and all the autopsy reports of gunshot or stab wound victims whose survival period satisfied criteria established for this study were reviewed. The data were compared to those from a similar study done in 1961. In addition, this study noted the presence and influence of drugs or alcohol on the cause of death and the postinjury survival time.

Adult↗

The maternity blues in post-partum and post-operative women.

In order to establish whether the maternity blues is peculiar to the puerperium a self-rating blues questionnaire was administered to women after childbirth and after surgery. A period of dysphoria, similar in many respects to the maternity blues, was experienced by women post-operatively. The main difference between maternity and post-operative patterns of dysphoria seemed to lie in the timing of the blues, but on closer analysis many post-operative dysphoric symptoms peaked in a similar way to those in the maternity group. In the search for the cause of the maternity blues it may be helpful to study the same parameters in post-operative dysphoria.

Adolescent↗

Seasonal fertility cycles in rural Egypt: behavioral and biological linkages.

The annual birth cycle in rural Egypt peaks in December and has two distinguishable minima in June and September. This pattern bears a striking inverse resemblance to the seasonal movements of employment and wages. Infant and child mortality and marriage also display stable, though different seasonal patterns. The paper explores whether the correlation between labor demand, mortality events and fertility reflect some causal behavioral relationship. It is shown that the probability of a birth is lower in months with high opportunity cost of time. Direct replacement is a significant phenomenon in rural Egypt and it occurs fairly quickly.

Birth Rate↗

[Evaluation of a long-acting neuroleptic: penfluridol. Clinical and psychosocial evolution at a year follow-up].

Twenty schizophrenic patients were treated for a year with long term neuroleptic Penfluridol to test its antipsychotic and re-socializing effect. They underwent a clinical follow up and an evaluation of psychosocial aspects was also performed by a psychiatric social worker. Their social behaviour and reinsertion to work and family were studied by the use of specially designed scales. Clinical improvement and significant changes in all of the studied aspects of social behaviour were observed after a year of treatment. Also a reduction of treatment abandonment and of frequency of relapse through family handling was detected. Finally a number of preliminary observations on family structure and dynamics as well as changes determined on it by the treatment of the psychotic patient are summarized.

Adolescent↗