The authors present a case of a parosteal osteosarcoma of the fourth metatarsal in a 19-year-old male. This location has never been previously reported. The periosteal new bone formation without bone destruction must be differentiated from foreign body reaction and stress fractures. En bloc resection of the fourth and fifth rays was done. There has been no evidence of recurrence to date, 1 year and 10 months following the surgery. There has been an excellent functional result.

Adult↗

PubMedDate not supplied

Fine detail radiography of the femoral head in osteoarthritis.

In an effort to define the relationship of articular cartilage to subchondral bond in osteoarthritis, fine detail radiography of over 600 femoral heads were examined. In general, cartilage loss was paralleled by subchondral bone thickening, but this was not a uniform finding. In the inferomedial part of the femoral head, thickening of the subchondral bone plate never occurred. If the cartilage thickening in this area exceeded 2 mm then a new subchondral bone plate was formed.

Calcinosis↗

PubMedDate not supplied

Autoimmunity in degenerative disk disease. A histopathologic study.

Recently, on the basis of in vitro experiments, a number of workers have suggested that degenerative disk desease may have an autoimmune basis. In order to corroborate these findings, a histopathologic study was undertaken on 218 specimens. A series of 108 Schmorl's nodes and 110 intervertebral disks obtained at laminectomy were examined for an immune-reaction type of inflammatory cellular infiltrate. While no inflammatory cellular infiltrates were found in any of the specimens, there were granulation tissue ingrowths and vascular invasion. these pathologic findings may represent the body's response to mechanical injury rather than in inflammatory response to a thus far undefined antigen.

Autoimmune Diseases↗

PubMedDate not supplied

Collapsed vertebrae: a review of 659 autopsies.

One hundred and thirty-three cases showing collapse of one or more vertebral bodies were found in a review of 659 autopsy specimens of the thoracolumbar spine. There are 4 types of vertebral body collapse; 2 of the 4 have clinical significance.

Adult↗

PubMedDate not supplied

Septic arthritis due to saccharomyces species in a patient with chronic rheumatoid arthritis.

Explore the source record for details and available documents.

Aged↗

PubMedDate not supplied

Microscopic anatomy of a femoral head after resurfacing arthroplasty: a case report.

The femoral head was removed after delayed sepsis in a resurfacing arthroplasty in a 50-year-old woman 12 months postoperation. Histologic sections showed intimate bonding between the femoral cup, cement and subjacent bone without evidence of excessive resorptive activity. The femoral head appeared viable within the cup and showed osteoblastic activity. The layers of fibrous tissue interposed between cement and bone appear to be a stage in the reparative process leading to effective anchoring of the cup rather than being a step toward bone resorption and loosening of the cup. A viable femoral head with an adequate blood supply is essential for healing of resurfacing arthroplasty. Osteogenesis in the resurfaced femoral head may be the important factor in the long-term success of an arthroplasty. Adequate blood supply may prevent avascular necrosis and subsequent "collapse".

Female↗

PubMedDate not supplied

Mesenchymal chondrosarcoma: a report of 17 cases.

Mesenchymal chondrosarcoma is a rare, almost uniformally lethal variant of chondrosarcoma which has been regarded as resistant to chemotherapy and radiotherapy. Seventeen cases are reported; 14 are dead of tumor or still alive with disease; eight of the 14 died less than one year after treatment, predominately of distant metastatic disease. This confirms previous reports of the highly aggressive nature of mesenchymal chondrosarcoma. Although surgery is regarded as the major method of treating the primary disease, it has limitations because many tumors cannot be adequately removed owing to location or extension to unresectable sites. It was found that such tumors respond to irradiation and that a combination of chemotherapy and radiotherapy should be used in unresectable tumors or those resected with inadequate margins. Adjuvant chemotherapy is advised in all cases treated with radical surgical excision. Unfavorable prognostic factors in mesenchymal chondrosarcoma are pain as a presenting symptom and a central rather than a peripheral limb location.

Adult↗