Search PubMed⌕ Search

Biomedical subjects

V Krcmery

Publications and source records attributed to V Krcmery.

At least 109 records · Page 6Linked to original sources
PubMed1995

Nosocomial bacterial and fungal meningitis in cancer patients.

Five cases of nosocomial meningitis are described that occurred within 5 years in a national cancer center in neutropenic cancer patients after cytotoxic chemotherapy: one caused by the yeast Aureobasidium mansoni and four caused by bacteria (two by Enterococcus faecalis and one by Salmonella enteritis and Arcanobacterium haemolyticus. Despite the severe symptoms, all cases were cured with appropriate antimicrobial therapy.

Adult↗
PubMed1977

Transduction, by phases F116 and G101, of gentamicin-tobramycin resistance, and of "autoplaque formation" property in Pseudomonas aeruginosa.

Pseudomonas aerugionsa phages F 116 and G 101, propagated on ML 4262 strain into which gentamicin-tobramycin resistance determinants have been increased by means of conjugation, from wild-type strains Vy 28, 29 and 34, were capable to transduce R determinants to PAO 1670 strain. Transfer ability was co-transduced as well, with exception of transductants selected with streptomycin. "Autoplaque formation" ability, occurring in original wild-type strain Vy 28, could be co-tranduced with all tobramycin-resistant determinants by F116 but not G 101 phage.

Anti-Bacterial Agents↗
PubMed1975

R factor-mediated resistance to aminoglycoside antibiotics in Pseudomonas aeruginosa.

Conjugal transferability of drug resistance was examined, in eleven Pseudomonas aeruginosa strains which were isolated in Frankfurt. Four R factors were demonstrated from three strains using P. aeruginosa as recipients but they were nontransferable to Escherichia coli K12. Two R factors, i.e., Rms146 and Rms147, mediated resistances to tetracycline (TC), streptomycin (SM), sulfanilamide (SA), kanamycin (KM), lividomycin (LV), gentamicin C complex (GM) and 3', 4'-dideoxykanamycin B (DKB). They mediated the formation of aminoglycoside-inactivating enzymes, i.e., SM phosphotransferase, SM adenylyltransferase, KM and LV phosphotransferase l, and GM and DKB 6'-N-acetyltransferase. TC resistance conferred by these R factors was due to impermeability of the drug. P. aeruginosa Ps 142 carried two kinds of R factor in one cell, Rms148 (SM) and Rms149 (SM-SA-GM-CPC) (CPC, carbenicillin). Rms148 (SM) was transferable at a high frequency of 10-1 and mediated the formation of SM phosphotransferase. Rms149 mediated the formation of drug-inactivating enzymes, ie., GM 3-N-acetyltransferase and beta-lactamase, but did not inactivate SM. SM resistance was probably due to impermeability of the drug.

Acetyltransferases↗