Search PubMed⌕ Search

Biomedical subjects

V Koleva

Publications and source records attributed to V Koleva.

13 recordsLinked to original sources
PubMed2006

[Cytolytic vaginosis--clinical and microbiological study].

47 women at reproductive age were diagnosed with cytolytic vaginosis according to their clinical and microbiological findings, including abundant lactobacilli/score 0 by Nugent/, free nuclei due to cytolysis, paucity of leucocytes, over 200 colony of HP/+/Lactobacillus spp., but no fungal growth. Heavy growth of HP/+/Lactobacillus spp. creates conditions under which the intensified cytolysis, displayed as abundant fluor, is likely to be due not only to the increased quantity of lactic acid but as well as to hyper production of hydrogen peroxide. 32 patients report improvement of their condition after at an average of 2 cycles of vaginal douches with sodium bicarbonate.

Colposcopy↗
PubMed2002

Infrared study of some synthetic phases of malachite (Cu2(OH)2CO3)-hydrozincite (Zn5(OH)6(CO3)2) series.

Synthetic malachite, hydrozincite and five monophasic mixed copper-zinc hydroxycarbonates have been studied by Fourier transform infrared (FTIR) spectroscopy at ambient and liquid nitrogen temperature in the region of 4000-400 cm(-1). The analysis of the spectra reveals that the samples containing up to 20% zinc retain the malachite lattice, thus forming solid solutions. The inclusion of zinc ions in malachite reflects on the positions and intensity of the bands corresponding to the internal modes of the carbonate ion, to the OH librations and to the Me-O interactions. For example, the higher and the lower frequency components of v3 shift to higher and lower frequencies, respectively. The intensity of the bands corresponding to v2 decreases with the zinc content increase. The spectrum of the sample Cu1.31Zn0.69(OH)2CO3 become diffuse and ill-resolved in the region of the Me-O interactions (region below 600 cm(-1)) and the corresponding bands are shifted to lower frequencies due to the weaker Zn-O interactions as compared with those of the copper ions. The internal modes of the carbonate ions in hydrozincite and aurichalcite are assigned and discussed taking into account the site symmetry and factor group symmetry. The OH and OD stretches (matrix-isolated HDO molecules) and the hydrogen bond strengths are interpreted in terms of Me-O interactions (synergetic effect), hydrogen bond angles and different hydrogen bond acceptor strengths of the oxygen atoms from the carbonate ions. It proves that the hydrogen bonds in hydrozincite are stronger as compared with those in malachite, irrespective of both the larger hydrogen bond lengths and the weaker Zn-O interactions in hydrozincite due to the higher hydrogen bond acceptor strength of the non-coordinated oxygen atom and the formation of bifurcated hydrogen bonds.

Carbonates↗
PubMed2001

Infrared spectroscopic study of mixed copper-cobalt and copper-nickel formate dihydrates (cation distribution in mixed crystals).

The infrared (IR) spectra of Co(HCOO)2 x 2H2O, Ni(HCOO)2 x 2H2O and Cu2Co(Ni)1-x (HCOO)2 x 2H2O mixed crystals (0 < x < or = 0.5) have been recorded and the internal modes of the formate groups and the water molecules are discussed. The analysis of the spectra of the mixed crystals reveals that when copper ions replace cobalt and nickel ions in Co(HCOO) x 2H2O and Ni(HCOO)2 x 2H2O, the Cu2+ ions are localized at the two available positions. However, the occupancy degree of the Me(1) and Me(2) sites by the different cations needs X-ray diffraction (XRD) studies of the single crystals. The new crystal phase Co0.17Cu0.83(HCOO)2 x 2H2O obtained from the Co(HCOO)2 x 2H2O-Cu(HCOO)2 x 2H2O-H2O system at 50 degrees C crystallizes in the monoclinic system with lattice parameters: a = 12.329(4); b = 7.241(2); c = 8.707(5) A and beta = 103.13(3) degrees (SG probably P2/c). The number of the bands corresponding to the uncoupled OD vibrations and the water librations shows that probably more than two water molecules are expected to exist in the structure. Furthermore, it is assumed that the water molecules bonded to the copper ions form stronger hydrogen bonds (stronger Cu-OH2 interaction) than those bonded to the cobalt ions.

Cations↗
PubMed2001

Changes in plantar pressures during bipedal stance with different stance width.

We studied the influence of stance width and vision on the plantar pressures for the left and right foot during bipedal quiet standing on the pressure-sensitive insoles. The support widening shifted the left and right centers-of-foot-pressure (CFPs) laterally and forward (right foot), diminished SDs of: the left and right mean plantar pressures (MPPs), the anteroposterior and mediolateral displacements of left and right CFPs. It also decreased negative correlations between left and right MPPs and between mediolateral displacements of left and right CFP and increased positive correlation between anteroposterior displacements of left and right CFPs, more expressive with eyes-open. The later results suggested that support widening increased the weight of exploratory behaviour regarding anteroposterior equilibrium and decreased exploratory sway serving mediolateral equilibrium. Eyes' closure lead to a small left bias of the body-weight-bearing and forward shift of the left versus right CFP, thus suggesting that vision increased bilateral symmetry of stance.

Adult↗
PubMed2000

[Hyperplastic and metaplastic changes of the endometrium].

The hyperplastic and metaplastic changes of the endometrium most often coexist and are associated with hyperestrogenic status--exogenous hormones, hormoneproducing ovarian tumors, persisting anovylatory cycles, PCOS. The correct histologic diagnosis of metaplasia and the differential diagnosis with atypical hyperplasia and some types of endometrial carcinomas, especially in cases of pre-operative curettage specimen, are of greatest importance for the consecutive therapeutic approach.

Anovulation↗
PubMed1998

[The concentration of selenium in the maternal serum in cases of missed abortion].

The changes in the serum level of selenium in cases with pathologic pregnancies are still not clear. The aim of the present study was to determine whether serum selenium in cases with missed abortion differed from selenium concentration in serum during first trimester of normal pregnancy. Twenty-three women with missed abortion and 61 with normal pregnancy were included in the study. We found a statistically significant (p < 0.001) elevation of serum selenium level in cases with missed abortion (928 +/- 335 nmol/l) comparing with those with normal pregnancy (568 +/- 77 nmol/l). We discuss the possible mechanisms of the observed changes.

Abortion, Missed↗
PubMed1998

[Pelvic actinomycosis].

Actinomycosis is an uncommon inflammatory disease of the female genital tract predominantly affecting the upper sections. Its appearance is in close connection with expended use of different IUDs. Its histological demonstration needs the detection of the specific sulphur granules. Because they often are rare it is recommended working of 8-12 paraffin blocks from suspected cases. The exact diagnosis is of high significance for preventing possible recivides after surgical intervention.

Abscess↗
PubMed1997

[Fetal diaphragmatic hernia. Concomitant anomalies].

According to different investigations congenital diaphragmatic hernia (CDH) is associated with other anomalies in 29% to 53%. The aim of our study was to present our experience with the prenatal diagnosis of CDH and to analyse the associated anomalies. For a ten-year period there were 18 fetuses born after 24 gestational week with CDH. The associated anomalies were found in 66.7%, most common they involved the nervous system, the heart and the kidneys. Our results confirm that there is a concentration of the most severe and with the worst prognosis cases of CDH in the bid neonatal centers.

Abnormalities, Multiple↗
PubMed1997

[The prognostic indices in congenital diaphragmatic hernia. Its management].

The reported mortality for prenatally detected congenital diaphragmatic hernia is high. We retrospectively reviewed 18 cases of congenital diaphragmatic hernia diagnosed prenatally in our hospital and analyzed several high-risk factors adversely affecting outcome. The diagnosis before 32 weeks gestation is associated with high mortality than in cases detected later. Polyhydramnios and underdevelopment of left-side cardiac structures were found to be helpful prognostic factors. These should be taken into account when the management of these cases is planed.

Bulgaria↗
PubMed1997

[The copper concentration in the maternal serum in missed abortion].

Two groups of women with missed abortion examined in different periods of time were included in the study--the first group of 43 patients was examined in 1989-1990 and the second group of 24 in 1994. The control group consist of 73 women in the first trimester of normal pregnancy and 75 nonpregnant women. The serum copper concentration of the first group with missed abortion (19.47 +/- 4.62 mumol/l) was significantly (p < 0.001) lower than those of control group with normal pregnancy (23.40 +/- 5.10 mumol/l). The serum concentration of the second group with missed abortion was even lower--17.82 +/- 2.95 mumol/l. The serum copper level was measured directly with flame atomic absorption spectrometry. The histology reveals dystrophic and necrotic changes and also inflammatory changes with edema of chorion villi without enhanced collagenisation. We discuss the possible mechanisms of the observed changes.

Abortion, Missed↗
PubMed1996

[Immunohistochemical studies of the pancreas in newborns with diabetic fetopathy].

The number and the size of the Langerhans islets in the pancreata of most of investigated cases with diabetic foetopathy is increased (polynesia and macronesia). The B endocrine cells are immunoreactive for both insulin and IAPP, the reaction for IAPP being weaker in comparison with the controls. In one of the cases (the mother with long history of treated type 1 diabetes, who died during delivery) no presence of insulin-immunoreactive of PAF positive B cells is discovered. The reactivity for glucagon and somatostatin in the pancreata with diabetic foetopathy is found to be similar to the controls. In the vicinity of some islets lymphoid cell infiltrations are observed.

Amyloid↗
PubMed1979

[Electrocardiography with the use of the orthoclinostatic test in the diagnosis of extrasystolic arrhythmia in childhood].

The differential-diagnostic importance of some ECG criteria and results of orthoclinostatic test in distinguishing functional form organic extrasystolic arrhythmias in childhood is appraised. Among the electrocardiographic indices the coupling interval is of great importance in differential diagnosis. Left-ventricular extrasystole is mostly encountered in rhythm disorders of functional origin. The data of the orthoclinostatic test are highly reliable in distinguishing functional disorders of rhythm from organic disorders.

Cardiac Complexes, Premature↗