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Biomedical subjects

V K Mittal

Publications and source records attributed to V K Mittal.

At least 37 records · Page 2Linked to original sources

Use of EEA stapler in reconstruction after gastric resection.

Herein is described our technique and experience with the EEA stapler in performing the Billroth I and II gastrectomies and Roux-en-Y reconstructive procedures. We did not perform a gastrotomy or an enterotomy to achieve the desired end to end or end to side anastomosis, thus avoiding another site to be closed later. In its single application, the EEA stapler gives a double layer of staggered staples, which results in a uniform and satisfactory healing. The removal of a ring of tissue with a central core, with examination for its completeness, assures a satisfactory anastomosis. The completed anastomosis can be examined under vision for any bleeding. As a final step, a TA 90 stapler is used at the desired line of transection of the stomach. This method of intestinal anastomosis shortens the operative time and creates a better anastomosis. We have performed these procedures upon 33 patients with good results.

Anastomosis, Roux-en-Y↗

Angiodysplasia in transposed colon.

A 40-year-old man with a history of colonic transposition for lye stricture at 10 years of age presented with upper gastrointestinal tract bleeding due to angiodysplasia in a transposed right colon.

Adult↗

Procurement and workbench procedures in preparation of pancreatic allografts. Factors essential for a successful pancreas transplant.

The rapidly developing field of pancreas allotransplantation can be regarded as an excellent school of surgery in which the topics of meticulous surgical technique and attention to detail by virtue of their significance strongly outweigh all other topics. The growing experience of the rather grave complications after pancreas transplantation points to the need for consistent use of meticulous techniques during organ procurement and application of workbench procedures just prior to transplantation. In addition, with the further development of the extra-renal transplant programs, the procurement of multiple organs from the same donor is becoming more common and the pancreatic team is more frequently faced with a less than optimal situation in regard to the vascular supply of the pancreatic graft. It, therefore, becomes imperative to carefully evaluate the vasculature and to make the necessary modifications prior to transplantation, since the best surgical techniques will not outweigh the consequences of a suboptimal blood supply, which will compromise the viability of any segment of the delicate pancreaticoduodenal graft.

Humans↗

Neutron activation analysis of trace elements in human hair: effect of dietary and environmental factors.

Effect of environment and dietary habits on trace element contents in human scalp hair has been investigated in the present work. Trace elements were detected with neutron activation technique. It was found that diet and environment contribute largely towards the trace elements in human body. Further trace elements Te, Lu, Ba, Cs, Yb, Re, Hf, In and Ir were detected for the first time in human scalp hair.

Adolescent↗

Pancreas transplantation--the Detroit experience (Mount Carmel Mercy Hospital).

In our preliminary series of pancreas transplants, the best results were obtained when kidneys were transplanted with pancreas allografts. The use of CyA together with combined kidney and whole pancreas transplants has significantly improved the graft survival in our program. It is difficult to draw conclusions as to the best technique for ductal management with the limited number of patients in each group. However, in our experience, ductocystostomy and pancreaticoduodenocystostomy have so far yielded the best results. Pancreaticocutaneous fistula with delayed ductal occlusion yielded the worst results and is not recommended. The effect of pancreas transplantation on the secondary complications may not be well discerned at this point in time until more long-term survivors are obtained. Some of our current results reflect the acceptance of high-risk transplant candidates into our program as well as the search for an improved pancreatic drainage technique.

Adult↗

Role of immediate versus delayed nephrectomy for failed renal transplants.

The role of timing of transplant nephrectomy after renal transplantation has not been well defined. This report compares the morbidity, mortality, and hospitalization costs of 37 patients undergoing transplant nephrectomy within 14 days after graft failure and return to dialysis, with 31 patients undergoing delayed transplant nephrectomy (less than 14 days after graft failure and return to dialysis). This analysis revealed that there were no significant (P greater than .05) differences in patient morbidity and mortality between these groups. There was, however, a substantial increase (P less than .05) in the cost of hospitalization in the delayed nephrectomy group. For this reason, we recommend early nephrectomy after renal transplant failure in order to minimize the cost of health care for these patients undergoing failed cadaver donor transplant nephrectomy.

Costs and Cost Analysis↗

Management of exocrine secretions in pancreatic transplantation: a new technique.

The management of exocrine secretions in pancreatic transplants remains an obstacle to success. This report describes an alternative approach for handling this problem. The technique includes a pancreaticocystostomy and occlusion of the accessory pancreatic duct prior to transplantation of the pancreatic graft. Thus far, acceptable results have been obtained by using this method in two whole pancreas transplant cases.

Cadaver↗

Celiac-superior mesenteric artery anastomosis in pancreatic transplantation: a new technique.

In whole organ pancreas transplantation, the vascular anastomosis is routinely based on the portal vein and a Carrel patch of the aorta containing the origin of the celiac artery and superior mesenteric artery. For end-to-side anastomosis to the external iliac, extensive dissection is necessary. A new technique involving bench surgery has been developed to avoid this large anastomosis between the Carrel patch and the external iliac artery. The single artery end-to-side anastomosis is accomplished between the distal end of the superior mesenteric artery and the external iliac, after anastomosis of the celiac artery to the proximal end of the superior mesenteric artery.

Cadaver↗

Myocardial contusion following nonfatal blunt chest trauma.

Currently available diagnostic techniques for myocardial contusion following blunt chest trauma were evaluated. We investigated 30 patients prospectively over a period of 1 year for the presence of myocardial contusion. Among the 30 patients, eight were found to have myocardial contusion on the basis of abnormal electrocardiograms, elevated creatine phosphokinase MB fraction (CPK-MB), and positive myocardial scan. Myocardial scan was positive in seven of eight patients (87.5%). CPK-MB fraction was elevated in four of eight patients (50%). Definitive electrocardiographic changes were seen in only two of eight patients (25%). It appears that myocardial scan using technetium pyrophosphate and CPK-MB fraction determinations are the most reliable aids in diagnosis of myocardial contusion following blunt chest trauma.

Adult↗

Cadaver kidney allograft survival in a high-risk black population utilizing antilymphoblast globulin and low steroid therapy.

This study contrasts graft and patient survival in black and white high-risk populations receiving cadaveric renal allografts. In addition, factors affecting the outcome of black and white high-risk patients maintained on chronic hemodialysis for one year are studied. While immunosuppression and treatment of rejection with ALG appeared to improve graft and patient survival of both black and white allograft recipients, high-risk black patients tended to do poorly on chronic hemodialysis. Black high-risk patients, therefore, may be better candidates for transplantation.

Antilymphocyte Serum↗