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Biomedical subjects

V K Kovalev

Publications and source records attributed to V K Kovalev.

13 recordsLinked to original sources
PubMed1989

[The initial forms of rectal cancer].

The paper discusses the tumor characteristics and long-term results of treatment of 6875 cases of rectal cancer admitted to oncological institutions of the USSR within 1968-1980. Stage I-IIa ("minimal") tumors were detected in 9.4% of patients. Organ-saving procedures (local excision included) were performed in 57%. Five-year actuarial survival following surgery was 63% according to the All-Union Center for Research on Effectiveness of Cancer Treatment and 74%--according to the N. N. Petrov Research Institute of Oncology data.

Adult↗
PubMed1988

[Treatment of cancer of the rectum by electrocoagulation].

The destruction of rectum carcinoma by electrocoagulation can be used for the treatment of patients of older age groups with high operative risk having exophite tumors of the inferior ampular part not more than 3 cm in size. When observing the conditions concerned and careful dispensary examination, the efficiency of immediate and long-term results of this operation are not inferior to generally used routine methods of treatment. Electrocoagulation of rectum carcinoma must be fulfilled but at oncological and specially equipped oncoproctological units.

Age Factors↗
PubMed1988

[Diagnostic significance of lymphoscintigraphy in cancer of the rectum].

Lymphoscintigraphic data were compared with the results of morphologic examination of resected regional lymph nodes in 51 cases of rectal cancer. Radionuclide method accuracy proved to be 80%, specificity--65% and sensitivity--96%. Correct diagnosis of metastasis was made in 73% while absence of metastases was reliably confirmed in 94%.

Humans↗
PubMed1987

[Diagnostic errors and inadequate therapeutic tactics in tumors of the large intestines].

The authors observed 21 patients after previous non-radical treatment in other medical institutions. The age of the patients was from 38 to 80. Radical operations were performed on all the patients during relaparotomies. The authors make a conclusion that choice of a rational surgical and curative tactics in colonic tumors was determined individually with special reference to the general state of the patient, careful assessment of the degree of local spread of the tumor. A dogmatic approach is thought to be inadmissible.

Adult↗
PubMed1985

[A method of treating villous tumors of the rectum].

A method of dissection of the rectum mucosa together with the tumor is described. The mucosa defect is closed by bringing the mucous membrane down and putting stitches on all the circumference. Successful operations were performed on 7 patients.

Female↗
PubMed1984

[Clinical manifestations of squamous cell carcinoma of the rectum].

The report deals with an evaluation of the data on 107 cases of squamous cell carcinoma of the rectum. 63 patients (58.8%) had proctological diseases in their case histories. Anal carcinoma is being misdiagnosed at out-patient hospitals as some other proctologic lesion in 34.9%. This fact points to the staff's lack of knowledge of the clinical picture of squamous cell carcinoma of the rectum. Abdominal-perineal extirpation of the rectum was the most frequent procedure used in the treatment of squamous cell carcinoma.

Adenocarcinoma↗
PubMed1982

The relation between the status of adaptive system and the number of postoperative complications in patients with gastrointestinal cancer: the effect of phenazepam.

The decrease in 11-hydroxycorticosteroids concentration caused by 0.5 mg of dexamethasone administered at 11 pm was studied in 91 primary patients suffering from gastrointestinal cancer. In dexamethasone-resistant patients postoperative complications developed in 65% of colon cancer patients and in 42% of stomach cancer patients. In dexamethasone-sensitive patients the complications were observed in 24% and 12% of patients, correspondingly. The elevation of hypothalamic threshold of sensitivity to the inhibiting effect of glucocorticoids, revealed by the dexamethasone suppression test, was considered to be as result of a combined action of age, the tumor itself, and pronounced emotional stress during the preparation for operation. The derivative of benzodiazepin--phenazepam--when administered before the operation in colon cancer patients improved the results of the dexamethasone suppression test and decreased the number of postoperative complications.

11-Hydroxycorticosteroids↗
PubMed1980

[Urolithiasis].

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Colic↗