[Elaboration of a passive avoidance conditioned defensive reflex in rats].
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Animals↗
Biomedical subjects
V K Fedorov
Publications and source records attributed to V K Fedorov.
[The relationship between short-term and long-term memory in the learning process of rats].
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Animals↗
[Mathematical model of the dose-time-effect relationship in the intramuscular administration of testosterone esters].
Two equations of the dose-time-effect dependence during repeated intramuscular injections of testosterone esters are presented. The equation coefficients characterizing both properties of the drugs injected and individual features of the organs exposed to their action are interpreted. Moreover, two equations for calculating duration of the mitotic cycle of the test organ cells are given.
Animals↗
[Determination of phospholipase A2 activity in liver mitochondria using fluorescent dye 1,8-anilinonaphthalene sulfonate].
Quantitative estimation of free fatty acids was carried out in liver mitochondria of normal and thyroidectomized rabbits by means of two procedures--spectrophotometry using rhodamine 6Zh and a fluorescent method with 1,8-aniline naphthalene sulfonate /ANS/ as a dye. The use of ANS enabled to estimate quantitatively the free fatty acids beginning from 25 nmol in a sample /with eggor of about 17%/ by visual evaluation of the spot areas. As compared with the rhodamine procedure, use of ANS permitted to increase 5-fold the sensitivity of free fatty acid estimation, to elevate 6-fold the accuracy of the analysis, to overcome the step of fatty acid elution from chromatogramms and to decrease the time required for analysis. The data obtained suggest that the hyperthyroid state in rabbits was accompanied by an increase in the phospholipase A2 activity in liver mitochondria.
Anilino Naphthalenesulfonates↗