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Biomedical subjects

V Jezek

Publications and source records attributed to V Jezek.

At least 73 records · Page 4Linked to original sources
PubMed1980

Long-term development of pulmonary hypertension in cryptogenic fibrosing alveolitis.

Values characterizing the central haemodynamics in patients with cryptogenic fibrosing alveolitis tend to vary considerably in the individual subjects over the years, but the long-term average indicates a trend towards a gradual deterioration. In most patients, the development of pulmonary hypertension is rather slow, amounting to 0.712 kPa (1.3 mmHg) per year on the average. This development is due both to the increase of the transpulmonary driving pressure gradient and to an increase in the pulmonary artery wedge pressure.

Adolescent↗
PubMed1980

Haemodynamic reaction to exercise and increased afterload in the detection of right heart failure in pulmonary diseases.

The effect of steady-state exercise and of increased afterload by angiotensin infusion on the right ventricular function was examined in 21 patients with chronic obstructive lung disease (COLD). 15 of them were always free from cardiac failure and 6 of them have had clinical signs of failure at the time of examination. Despite significant differences in various parameters between compensated (C) and decompensated (D) subjects, only the right ventricular filling pressure during both experimental procedures was able to differentiate the majority of individual C and D patients. The authors discuss the mechanisms of haemodynamic response to both stress tests and their significance for clinical evaluation of patients with COLD and for research into right ventricular contractility.

Adult↗