[Diseases of the tongue (author's transl)].
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Humans↗
Biomedical subjects
V Jahnke
Publications and source records attributed to V Jahnke.
[Rhinophyma. Etiology and therapy (author's transl)].
The characteristic signs of the nose in old age are referred to and comments made on their correction, which offers a possibility for prevention of psychic disorders. Moreover, the clinical picture of rhinophyma is presented, which only occurs in middle age and older people. These changes make the whole face look older and may also lead simultaneously to obstructed nasal breathing.
Aged↗
[Experiences using combination chemotherapy with cis-platinum, bleomycin and methotrexate in the management of advanced squamous cell carcinomas of the head and neck (author's transl)].
21 patients with unresectable or previously treated squamous cell carcinomas of the head and neck were treated with combination chemotherapy using cis-platinum, bleomycin and methotrexate. On day one of treatment, patients were given bleomycin (15 mg/M2) and methotrexate (20 mg/M2). On day two, a high dose of cis-platinum (120 mg/M2) was given. Up to five courses of therapy were given, with at least three weeks used as intervals between treatment. This therapy was tolerated by all patients, inclusive of the elderly and debilitated. Toxicity associated with this regimen was found to be more acceptable, and the tumor response considerably better than with the use of bleomycin-methotrexate alone. The temporary tumor response rate was found to be 85%, with patient survival varying to 16 months. Our experiences with cis-platinum confirm those results previously reported from tumor clinics in the United States during the past several years.
Adult↗
[Xeroradiography (author's transl)].
Xeroradiography with its advantages of the broader recording latitude and "edge enhancement" effect producing a high local contrast, is a useful addition to conventional radiography. In Otorhinolaryngology, this method is particularly recommended for the lareral view of the neck, facial trauma, salivary gland problems, tumors of the pharynx and larynx and stenoses of the trachea. Especially useful are tomograms and the choice of positive or negative images. The disadvantage of xeroradiography is the higher radiation dose as compared with the conventional dose.
Aged↗
[Allergic reaction on the nasal mucosa].
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Capillaries↗
[Prenatal causes of sensorineural hearing loss in children (author's transl)].
Prenatal causes of sensorineural hearing loss in children may be genetic or nongenetic, the deafness occurs alone or with other abnormalities. In addition, there are prenatal causes of a sensorineural hearing loss which is of delayed onset postnatally. In this review only the better known causes are discussed in which the otorhinolaryngologist should establish a diagnosis early, particularly when the possibility exists of preventing or even treating the hearing loss.
Aminoglycosides↗
[ENT considerations of head and facial pain (author's transl)].
To the otolaryngologist, there are multiple causes for head or facial pain: headaches due to ear diseases; idiopathic neuralgias; "referred otalgia" involving cranial nerves V, IX, X; temporomandibular joint dysfunction; rhinological pathologies, including post-traumatic trigeminal neuralgia; "facial sympathalgias"; the styloid process syndrome; and cervical spine problems. Less known causes of head and neck pain are stressed, and emphasis placed on their diagnosis and treatment.
Facial Neuralgia↗
Electron microscopic study of the normal and allergic nasal mucosa.
Electron microscopic studies of the human nasal mucosa have complemented earlier histological and histochemical studies. In this paper, the fine structural details observed in different tissue components are described and discussed in relation to the function of the nasal mucosa under normal and pathological conditions. The physiological changes in the anterior part of the inferior turbinate which occur under the influence of air currents differ clearly from the electron microscopic picture of respiratory mucosa with typical ciliated epithelium. The fine structure of the allergic nasal mucosa differs according to the stage of the allergic reaction; the characteristic changes are described both after different time intervals following intranasal allergic testing with positive reaction as well as in patients with seasonal or perennial nasal allergy of longer duration.
Humans↗
[The 70th birthday of Hans Selye].
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Austria↗
[Electron microscopy of human nasal mucosa in disturbances of the autonomic nervous system. I. Sympathetic denervation (author's transl)].
The fine structure of the human nasal mucosa is described shortly after unilateral stellate gang-lion blockage as well as in a case of sympathetic denervation of four weeks duration. For the clinical picture, corresponding to vasomotor rhinitis, there is a characteristic fine structural correlation consisting of dilatation and increased permeability of the vessels as well as stimulation of the nasal glands. In the glands, both increased activity and degenerative changes suggesting "secretory exhaustion" are observed. The findings differ from those seen in acute and chornic allergic rhinitis, but correspond to those in experimental animals following the administration of parasympathicomimetic drugs.
Adult↗
[Facial and head pain from the otorhinolaryngologist's point of view (author's transl)].
From the otolaryngologist's point of view, there are multiple causes for the frequent symptom of facial and head pain: headaches due to ear diseases: pain extending to the ear region, with special regard to "referred otalgia" involving the cranail nerves V, IX, X; facial pain due to temporomandibular dysfunction; rhinological causes of facial and head pain, including posttraumatic trigeminal neuralgia and "facial sympathalgies"; the syndrome of the elongated styloid process. The diagnosis and therapy of the "typical" ENT diseases is not described in detail since the paper deals mainly with less known and, regarding their diagnosis and treatment, problematic diseases.
Acute Disease↗
[Reconstructive procedures in the oral cavity and oropharynx following tumor resection (author's transl)].
Even in far advanced carcinomas of the oral cavity and oropharynx (T3-tumors) with extensive resections there are methods of plastic reconstruction which provide an acceptable functional and esthetic result for most patients. For immediate reconstruction of the soft tissues the forehead flap of McGregor, the deltopectoral flap of Bakamjian and the posteriorly pedicled tongue flap are particularly useful. Following surgical removal of the chin portion of the mandible a titanium implant is recommended for immediate replacement. Inspite the advances in plastic reconstructive surgery, these procedures rarely lead to a five-year cure rate; regarding palliation and hope for cure they are more promising, however, than radiation therapy alone.
Female↗
[Fine structure of nasal mucosa in mucoviscidosis, with special regard to polyposis (author's transl)].
In mucoviscidosis, even the clinically and histologically often normal appearing nasal mucosa exhibits characteristic changes with the electron microscope. The epithelial cells show intra- and extracellular edema, the cilia membrane damage. The highly viscous mucous blanket and the frequent lamination of the basement membrane of the capillaries can be explained by a disturbance in mucopolysaccharide and glycoprotein metabolism respectively. The functional disorder of the goblet cells and the nasal glands manifests itself with signs of increased activity, but without definite degenerative changes. The course of the pathologic mucous formation on the cells appears morphologically normal so that a disturbance of membrane transport or in the dilution of the secretions must be assumed. The endonasal polyps differ from allergic polyps by the absence of eosinophilic infiltration.
Adolescent↗
[Electron microscopy of human nasal mucosa in disturbances of the autonomic nervous system. II. Parasympathetic denervation by vidian nerve transsection in vasomotor rhinitis (author's transl)].
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Adolescent↗
[Mistakes and dangers in the treatment of facial fractures].
On the basis of the general principles of treatment, the mistakes and dangers are described in the reduction of the following fractures: Nasal fracture and nasoorbital fracture, Le Fort fractures, malar fracture, zygomatic arch fracture, blow-out-fracture. For optimal functional and cosmetic results the collaboration of different specialities is necessary. Serious complications in the treatment of orbital floor fractures (optic nerve damage, increased intraorbital pressure with visual loss due to hemorrhage or edema) are discussed in detail. Late sequelae of unrecognized or faulty treated facial fractures are considered well as the dangers in the management of facial fractures in children.
Facial Injuries↗
[Fine structure of human nasal mucosa in acute allergic reaction (author's transl)].
The fine structure of the acute allergic reaction is described in the human nasal mucosa. Subsequent to intranasal allergic testing with positive reaction characteristic changes are seen after different time intervals: Massive transudation into the dilated intercellular spaces, loss of epithelial junctions, extrusion of epithelial cells into the nasal lumen; increase permeability of capillaries and venules with increase of fenestrations and pinocytotic vesicles, edema of the cytoplasm and dilatation of intercellular junctions in the endothelium. Characteristic for the later stages are pronounced lesions of the vessel walls with interruption of cell junctions interstitial edema. endothelial gaps and loss of endothelial cells. The endothelial basal membrane usually remains intact. The findings are compared with those described for the acute hyperergic reaction in animals and chronic allergic changes in the human nasal mucosa.
Acute Disease↗
[Morphology and clinical significance of syringomas of the external auditory canal (author's transl)].
Syringomas of the external auditory canal ("ceruminomas"), are very rare their morphology is varied and their clinical course hardly predictable. Their nomenclature is controversial and easily misunderstood. Two cases of syringomas of the external auditory canal are reported (one adenoma and one adenoid-cystic carcinoma) which were also studied by means of electron microscopy. The morphology and clinical significance of these tumors is discussed.
Adenoma↗
[Clinical, pathological and therapeutic aspects of cholesteatoma in children (author's transl)].
Middle ear cholesteatoma in childhood is discussed on the basis of 117 operated cases. Early diagnosis was rare, even after fetid otorrhea of long duration; occassionally they presented as acute mastoiditis. The cholesteatoma occurred mostly in older children (90%) and extended to the antrum (73%) or beyond it (54%), with destruction of the ossicles (77%); the hearing often remained normal. Tympanic membrane perforations were usually small, relatively often they were central. More than 50% of the children had normal mastoid pneumatization, usually there were no typical radiological signs of cholesteatoma. Tympanoplasty was most frequently type III (68.5%), the postoperative hearing gain in this group was 47.3%. Residual or recurrent cholesteatoma occurred in 8.5%.
Age Factors↗