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Biomedical subjects

V J Wilson

Publications and source records attributed to V J Wilson.

At least 109 records · Page 6Linked to original sources
PubMed1970

A short-latency labyrinthine input to the vestibular nuclei in the pigeon.

Electrical stimulation of the pigeon labyrinth evokes responses in many second-order vestibular neurons with a latency shorter than the monosynaptic delay. These early responses are probably due to electrically mediated synaptic transmission, or perhaps to antidromic invasion of cells supplying efferent fibers to the labyrinth. In either case the results demonstrate a difference between cat and pigeon with respect to connections between labyrinth and vestibular nuclei.

Animals↗
PubMed1966

Acetylcholine sensitivity of cerebellar neurones in the cat.

1. Cholinomimetics, acetylcholine antagonists and some other compounds of pharmacological interest were administered electrophoretically near neurones within the vermal cerebellar cortex of anaesthetized (pentobarbitone) and unanaesthetized (cerveau isolé) cats.2. The neurones were identified by position within the cortex, spontaneous activity, and the responses to afferent and antidromic stimulation.3. Purkinje cells, but neither granule nor basket cells, were excited by cholinomimetics, and the acetylcholine receptors had muscarinic properties. Excitation was often preceded by depression of the spontaneous firing.4. Intravenously administered atropine and dihydro-beta-erythroidine did not depress the synaptic excitation of cerebellar neurones evoked by impulses in mossy, climbing or parallel fibres.5. Acetylcholine is thus unlikely to be an excitatory transmitter within the feline cerebellum, particularly at mossy fibre-granule cell synapses, despite the presence of relatively high levels of acetylcholinesterase within mossy fibre terminals.

Acetylcholine↗