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Biomedical subjects

V J O'Conor

Publications and source records attributed to V J O'Conor.

At least 19 recordsLinked to original sources
PubMed1994

Use of electrocoagulation in the treatment of vesicovaginal fistulas.

The role of electrocoagulation for the treatment of vesicovaginal fistulas has not been clearly defined. To determine the use of this therapeutic modality, 15 cases of fistulas treated with electrocoagulation were retrospectively reviewed. Fulguration represented the primary treatment in 12 patients and the secondary treatment in 3 after an initial attempt at open surgical closure failed. In all instances fistula size was estimated to be 3.5 mm. or less. A Bugbee electrode, which was inserted into the fistula either cystoscopically or vaginally, was used to destroy the epithelial lining of the fistula tract. Following the procedure the bladder was decompressed with a large indwelling Foley catheter for at least 2 weeks. Fulguration was successful as the sole treatment modality in 9 of 12 patients (75%) and as an alternative intervention after failure of an open surgical repair in 2 of 3 (66%). Therefore, 11 of the 15 women (73%) had complete resolution of the fistulas with this technique. We conclude that fulguration is usually effective in managing patients with vesicovaginal fistulas a few millimeters in size or less. This technique should be used as an initial treatment for appropriately selected patients and in women with small residual fistulas after open surgical failure.

Electrocoagulation↗
PubMed1989

Transmission of nonA/nonB hepatitis during coagulation pyelolithotomy.

The use of coagulum for renal stone surgery is an important yet less frequently used tool in the urological armamentarium. We report the first documented case of transmission of viral hepatitis during coagulum pyelolithotomy. We review the basic tenets of its use, with a brief discussion of the blood-borne transmission of viral particles and risk of hepatic injury with volatile anesthetic agents, and propose the continued safe use of coagulum by autologous donation of cryoprecipitate.

Factor VIII↗
PubMed1987

A comparison of endoscopic suspension of the vesical neck with suprapubic vesicourethropexy for treatment of stress urinary incontinence.

To compare the efficacy of the Stamey endoscopic vesical neck suspension with the Marshall-Marchetti-Krantz vesicourethropexy in the correction of stress urinary incontinence, we studied retrospectively 127 consecutive patients who underwent either procedure during a defined interval at our institution. Of 95 women for whom adequate data were available 41 (group 1) underwent the Stamey and 54 (group 2) underwent the Marshall-Marchetti-Krantz procedures. Characteristics of the 2 groups were similar. A cure was obtained 21 to 118 months postoperatively in 61 per cent of the patients in group 1 and in 57 per cent in group 2. Cured and improved rates for the 2 groups were 78 and 80 per cent, respectively. Cure rates decreased with time in both groups. Complications occurred in 37.5 per cent of the patients in group 1 and in 18.5 per cent in group 2. Risk factors implicated in the pathogenesis of primary or recurrent stress urinary incontinence did not predispose to failure in either group. Adequate interpretation of our lower cure rates vis-à-vis those reported previously is hampered by the variability between series in the definition of cure and length of postoperative followup.

Cystoscopy↗
PubMed1981

Long-term survivor of prostatic carcinoma with lung metastases.

A patient with stage D2 carcinoma of the prostate is presented with biopsy-proved pulmonary metastases. Treatment consisted of hormonal therapy in the form of orchiectomy and ethinyl estradiol and he is alive 14 years later without evidence of disease. The pulmonary manifestations of prostatic carcinoma are discussed as well as the prognostic implications. This long-term survival, in view of the patient's initial presentation, makes this case unique.

Adenocarcinoma↗
PubMed1980

Review of experience with vesicovaginal fistula repair.

Experience with suprapubic closure of vesicovaginal fistulas in 42 patients considered candidates for this procedure is reviewed. Five patients required a second operation for cure and the reasons for failure are discussed. Wide exposure with tension-free closure of well vascularized flaps and the judicious interposition of pedicled omentum have produced the most encouraging results. The litigious nature of this distressing condition is lessened when primary closure is successful and supravesical diversion by ileal or colonic conduits can be avoided.

Female↗
PubMed1979

Review of experience with vesicovaginal fistula repair.

Experience with suprapubic closure of vesicovaginal fistulas in 42 patients considered candidates for this procedure is reviewed. Five patients required a second operation for cure and the reasons for failure are discussed. Wide exposure with tension-free closure of well vascularized flaps and the judicious interposition of pedicled omentum have produced the most encouraging results. The litigious nature of this distressing condition is lessened when primary closure is successful and supravesical diversion by ileal or colonic conduits can be avoided.

Adolescent↗
PubMed1977

Transurethral external sphincterotomy and its effect on potency.

A series of 43 male patients who underwent external sphincterotomy because of vesicosphincteric dysfunction is reviewed. There were 6 patients who subsequently noticed absence or a marked decrease in erectile ability. Various factors are considered that might have affected potency, and the theoretical reasons for this occurrence and subsequent recovery are discussed.

Erectile Dysfunction↗
PubMed1976

Silent hydronephrosis, a hazard revisited.

Six patients with neurogenic bladder secondary to spinal cord injury were seen in our Centre for routine follow-up. All of these individuals had attained the catheter-free state by various means and were, by their standards, functioning very well. They had gone from 6 months to 2 1/2 years without genito-urinary re-evaluations. One individual had a normal urogram 1 year after catheter removal and then 2 years later was noted to have bilateral hydronephrosis. Development of silent hydronephrosis in the catheter-free state, its treatment, and a regimen for following patients are discussed.

Humans↗
PubMed1975

The use of tetrazolium to determine hydronephrotic damage in human kidneys.

A study detailing an assay for evaluating hydronephrotic damage is presented. We used nitroblue tetrazolium, which is reduced by intact renal tissue. When marked hydronephrotic damage has occurred little evidence of tetrazolium reducing activity is present. The clinical application has been helpful in determining the extent of damage and the subsequent need for removal of the kidney in question. When the test indicated functioning renal tissue a repair of the obstruction was performed with subsequent improvement in function.

Biopsy↗