[Problems in curing diffuse toxic goiter].
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Adolescent↗
Biomedical subjects
V Ia Khramtsova
Publications and source records attributed to V Ia Khramtsova.
[Treatment of diffuse toxic goiter with radioactive iodine in combination with prolonged antithyroid therapy].
The authors analyzed clinically the results of treatment of 237 patients with diffuse toxic goiter with radioactive iodine in combination with prolonged antithyroidal therapy (12--18 months). The advantages of combined therapy consisted in the use of relatively low 131I doses, a great frequensy of clinical remissions of thyrotoxicosis (83%), in the absence of thyrotoxicosis remissions after the administration of a low radioactive iodine dose and a low percentage of stable hypothyroidism development (0.8%) as a complication of radioiodine therapy.
Adult↗
[Functional reserves of the thyroid gland in thyrotoxicosis remission].
A test with intramuscular injection of 5 or 10 U of TTH was carried out in 47 patients suffering from diffuse toxic goiter, including 34 cases at the stage of thyrotoxicosis remission. Results of this test were evaluated by the changes of I131 absorption by the thyroid gland and of the blood protein-bound iodine level. The thyroid gland TTH sensitivity was found to be diminished in 16 patients with thyrotoxicosis remission. The reaction was absent most regularly in patients with ophthalmopathy. This denotes a latent form of thyroid insufficiency and suggest that the patients with the negative response to the exogenous TTH are in the "risk group" in respect to the development of manifest hypothyroidism.
Adult↗