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Biomedical subjects

V I Titov

Publications and source records attributed to V I Titov.

At least 19 recordsLinked to original sources

[Reflected wave and isolated systolic hypertension: problems of pathogenesis and therapy].

The value of reflected (tidal) wave amplitude in the pathogenesis of isolated systolic hypertension (ISH) is discussed and main characteristics of elastic properties of arteries (compliance, distensibility, rigidity, pulse wave velocity, and amplitude of reflected wave) are considered. In ISH systolic and pulse blood pressures are associated with augmentation of the reflected wave amplitude. Increased pulse wave velocity characteristic of ISH leads to displacement of reflected wave from diastole to systole. Summation of two waves (primary and reflected) causes elevation of systolic blood pressure. Choice of antihypertensive drugs for the treatment of ISH is determined by their action on pulse wave velocity, delay of reflected wave and arterial compliance. Preferable agents are angiotensin converting enzyme inhibitors, calcium antagonists, diuretics and beta-blockers with vasodilating properties. In bradycardia with high stroke volume normalization of heart rate can be achieved by M-anticholinergic drugs and theophylline.

Antihypertensive Agents↗

[The treatment of patients with chronic obstructive bronchitis by using a low-power laser at a general rehabilitation center].

100 patients with chronic obstructive bronchitis were examined and treated in the therapeutic department of rehabilitation center. Combined treatment including low-energy laser radiation produced good results. Laser therapy has improved bronchial permeability, sensitivity of bronchial beta 2-receptors to sympathomimetics. As a result, their intake was reduced or discontinued. Laser radiation combined well with other non-pharmacological modalities.

Adult↗

[The relative role of hereditary and environmental factors in the formation of the maxillodental system].

The contribution of hereditary and environmental factors to the formation of maxillodental abnormalities in the ontogenetic aspect was analyzed using a twin model. A total of 80 twin pairs aged 3 to 18 were examined. The results permitted the authors define the age periods favorable for therapeutic and prophylactic measures in children with abnormalities of the teeth, dentition, and occlusion. Effects of sex dimorphism on the parameters of the maxillodental system at various stages of ontogenesis were studied. Sex-specific differences were found to augment with age; all the analyzed parameters in boys were superior to those in girls at the age when sex-specific factors completely exerted their effects on the maxillodental system at the period of permanent teeth occlusion.

Adolescent↗

[Analysis of the interaction of genotypic and paratypic factors in the development of maxillo-dental anomalies in ontogeny].

Component analysis of total phenotypic variance was used to analyze data on 80 pairs of twins aged 3 to 18 years, examined in the Stupino outpatient dental clinic, Moscow oblast. Genotypic and environmental factors are shown to play different roles in the development of abnormalities of teeth, dental arches, and occlusion at different ontogenetic periods of deciduous, mixed, and permanent dentition. Periods when paratypic factors prevailed were revealed. This made it possible to identity periods when prophylaxis and orthodontic treatment are the most advisable.

Adolescent↗

[The use of permanent magnets in the orthodontic clinic].

The author reviews published literature on the use of permanent magnets as an alternative to traditional methods of instrumental treatment in orthodontics. Use of magnetic technology in orthodontics should be further researched and improved.

Humans↗

[Moderate arterial hypertension during its natural course and in drug correction].

The clinical and morbid anatomy data on 295 patients with arterial hypertension were examined. Two hundred patients had moderate hypertension with the diastolic pressure under 110 mm Hg. Of these, 103 patients had received rauwolfia drugs and 13 patients had been given hypothiazide in addition. Eighty patients who died before 1953 had not received any specific hypotensive drugs. Early hypotensive therapy of moderate hypertension was noted to promote a decrease in arterial blood pressure to normal and to raise the mean lifespan by 8 years. Furthermore the number of fatal brain strokes and myocardial infarctions decreased almost 2-fold.

Blood Pressure↗