[Prevention and treatment of the incompetence of the esophageal anastomosis].
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Biomedical subjects
Publications and source records attributed to V I Rusakov.
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The article is concerned with difficulties of the treatment of urethra strictures, complicated in particular, and analyzes results of the surgical treatment resulting from localization of the stricture, its extension and the treatment method. The best results were obtained following resection of the urethra by Rusakov's method. From 65 operated children 59 patients showed complete recovery. The results were less consolatory when scrotum skin was used for the reconstruction of posterior urethra strictures of great extent.
The histophysiology of adrenals has been studied in the model of high strangulation acute ileus. Dramatic inhibition of the enzymatic system activity has been revealed as well at the development of acute adrenal insufficiency in the early terms of acute ileus. The terminal period (30--38 hours) is characterized by total necrosis of the adrenals.
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From 1955 to 1975 the author has treated 705 patients with stricture of the urethra. He has elaborated his own procedure consisting of radical excision of the stricture and scar tissues with end-to-end anastomosis. In cases of long strictures, reconstruction of the urethra has been by the use of a scrotal flap.
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Methyluracil doses from 1 to 50 mg/ml induced an increase of total nucleinic acids in the nuclei and the protein in the cytoplasm of the HEp-2 cells. 20 mg/ml of methyluracil gave a progressive increase in the nucleinic acid concentration in the cells--from 122 to 197 %. A relatively stable increase of protein at all the time intervals was induced by a dose of 30 mg/ml (132--145%). This is in favour of an increase in cell metabolic processes under the influence of methyluracil.
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