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Biomedical subjects

V I Medvedev

Publications and source records attributed to V I Medvedev.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Comparative activity of memory-modulating neuropeptides before and after electric shock in white rats.

Neuropeptides are shown to exert a powerful influence on mnestic processes. They actively eliminate phenomena of electric-shock amnesia, the strongest agent here being arginine vasopressin, while derivatives of oxytocin, enkephalin, and melanostatin are active to a lesser degree. The selective effect on primary learning (ACTH4-7 and Leu-enkephalin) and on the consolidation and restoration of memory (vasopressin and oxytocin), and the presence of only antiamnestic properties (analog of the melanocyte-inhibiting factor) - all this suggests different mechanisms of action of these agents. Memory modulators act more strongly upon activated systems that are already prepared to receive the signal. A promising object for future study as a therapeutic antiamnestic factor is the long-term memory modulator arginine vasopressin.

Adrenocorticotropic Hormone↗
PubMedDate not supplied

[Zinc content in pancreatic islets in experimental diabetes induced by chelating agents].

The zinc content in microresected islets of rabbits, mice, rats, and guinea pigs was determined by atom-absorption spectrophotometry. The content was found to be highest in rabbits, and diabetes was induced in them by chelating agents easily. Injection of dithizone or 8-(p-toluenesulfonylamine) quinoline failed to induce diabetes mellitus in mice, rats, and guinea pigs. It is concluded that diabetogenic chelating agents are capable of producing irreversible diabetogenic affection in those beta-cells which contain a critical concentration of reactant zinc.

Animals↗
PubMedDate not supplied

[Combined effect of detergents and priority pollutants on the body and quality of environment (review of literature)].

The paper deals with the topical problem in the combined effect of detergents and priority pollutants (pesticides, mineral fertilizers, and heavy pollutants) on the body and the quality of the environment. Under combined man-made environmental pollution, surfactants may substantially alter the behavior and toxicity of many chemical substances, which requires that these studies should be continued.

Animals↗