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Biomedical subjects

V I Gudim

Publications and source records attributed to V I Gudim.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Erythropoietin and erythropoiesis inhibitor in neonatal hypoxia and normal conditions].

In 22 healthy newborns and in 31 newborns with transposition of the major arterial vessels (TMAV) erythropoietin and erythropoiesis inhibitor was studied on a model of polycythemic mice. Erythropoietin was not detected, whereas erythropoiesis inhibitor was revealed in the plasma and urine of 5--7-day-old healthy newborns. The newborns with TMAV displayed a rise of erythropoietin level up to the 14th day and its reduction during the period of from 14th to the 56th days. Erythropoiesis inhibitor was also found in the urine concentrates of the newborn with TMAV during the period of 3--4 weeks. The role of erythropoiesis inhibitor as a physiological regulator appearing in the blood of healthy and hypoxic newborns to normalize the erythropoiesis in the course of the initial weeks after birth is discussed.

Erythropoietin↗
PubMed1975

Inhibitors of erythropoiesis in patients with aplastic anemia.

An inhibitor of erythropoiesis was found in the urine of patients with aplastic anemia. The inhibitor was concentrated with kaolin and separated from erythropoietin by subsequent fractionation with alcohol and gel filtration on Sephadex G-100 and DEAE-Sephadex A-50. The inhibitor blocked the effect of erythropoietin (standard C) when injected into mice with hypoxic polycythemia 3 H before or along with exogenous erythropoietin; partial neurtralization of standard C also was observed on incubation with the inhibitor.

Anemia, Aplastic↗