[Myocardial hypoxia in assisted circulation with total hemodilution].
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Biomedical subjects
Publications and source records attributed to V Holec.
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After two hours of immobilization stress in rats, the authors observed significantly decreased noradrenalin values in the myocardium, returning to normal values later. The concentration of adrenalin in the myocardium of rats showed a contrary behavior under stress conditions. Myocardiac catecholamin shifts in dogs with experimental stress induced by coronary occlusion were registered. After 120 minutes of mechanical circulatory support for the left-sided bypass system the catecholamin level in the left atrium decreased. On the other hand, catecholamin levels in the left ventricular myocardium, injured by experimental infarction, were unchanged after 120 minutes of assisted circulation. In correspondence with hemodynamic and metabolic findings, these results could support the method of assisted leftside bypass. Myocardial catecholamines seem to be another possible parameter for the assisted circulation.
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