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Biomedical subjects

V Herreros

Publications and source records attributed to V Herreros.

At least 19 recordsLinked to original sources
PubMed2001

Tularemia epidemic in northwestern Spain: clinical description and therapeutic response.

This study describes the clinical characteristics of tularemia in Spain's first epidemic outbreak and the therapeutic response and compares the efficacy of 3 antibiotics (streptomycin, ciprofloxacin, and doxycycline). For 142 cases of tularemia, the therapeutic failure rate was 22.5%; ciprofloxacin was the antibiotic with the lowest percentage of therapeutic failures and with the fewest side effects.

Adolescent↗
PubMed1997

Endocarditis caused by Enterococcus avium.

Enterococcus avium has rarely been reported as a pathogen in humans. We describe a case of endocarditis caused by E. avium. It responded to ampicillin and gentamicin, although a valve replacement was necessary for severe aortic insufficiency. This microorganism should be regarded as significant in endocarditis.

Endocarditis, Bacterial↗
PubMed1982

No correlation between iron concentration in breast milk and maternal iron stores.

The relation between the iron transmitted to infants by breast milk and the maternal iron stores was investigated in a group of 46 women. Total milk iron concentration was not correlated with the levels of serum ferritin or transferrin saturation. These results suggest that the iron transport from mother to the milk is irrespective to the maternal iron stores.

Adult↗
PubMed1982

Maternal and cord blood ferritin.

The levels of plasma iron, transferrin saturation and ferritin in cord blood of 64 newborns were found to be elevated relative to the corresponding maternal blood. There was no correlation between the levels of plasma iron, transferrin saturation or ferritin in cord and maternal blood. No correlation was found in cord blood between the hemoglobin levels or red cell indices (MCV, MCH and MCHC) with the levels of ferritin. These results suggest that there is an active process of transfer for iron from mother to the fetus, and this transport is independent of fetal erythropoiesis.

Female↗
PubMed1981

Clinical evaluation of simultaneously administered 58Co labelled vitamin B12 and 57Co labelled vitamin B12 bound to intrinsic factor in patients with pernicious anaemia.

The clinical and laboratory data from 75 patients with altered vitamin B 12 absorption were reviewed. In 36 cases the diagnosis of pernicious anaemia had been established. Of these, 14 patients showed malabsorption of radiolabelled vitamin B 12, but the absorption of vitamin B 12 bound to the intrinsic factor (IF) was normal (Group A). The other 22 patients with pernicious anaemia showed altered free and IF-bound vitamin B 12 absorption (Group B). Laboratory and clinical data and the absorption tests (xylose and fat excretion) were more abnormal in group B than in group A. Finally, 39 patients (Group C) with general malabsorption showed alternation of the absorption of free and IF-bound vitamin B 12 (Group C). The clinical nd biological data were different in these patients from that found in groups A and B. It is possible that in patients with pernicious anaemia who are untreated an alteration of the intestinal mucosa may produce a malabsorption of vitamin B 12 even in the presence of intrinsic factor.

Anemia, Pernicious↗
PubMed1981

Levels of serum ferritin, folate, and vitamin B12 in pregnant women at term who had been supplemented with iron and folate.

The levels of serum ferritin, folates, and vitamin B12 in relation to the hematologic values were measured in 66 pregnant women at term who had been supplemented with iron (100 mg/day) and folate (350 microgram/day). The levels of hemoglobin in pregnant women were similar to the controls;' however, levels of ferritin and transferrin saturation were decreased and showed a correlation with the hemoglobin. The MCV increased, whereas folate and vitamin B12 decreased, but no correlation was found between these values. These results suggest that in pregnant women (a) serum ferritin and transferrin saturation reflect the iron available for erythropoiesis, (b) the iron supplementation of 100 mg/day in the population studied is not sufficient, and (c) the macrocytosis is independent of the folate and vitamin B12 levels.

Adolescent↗
PubMed1980

Liver iron storage in Spanish aging population.

Liver samples were collected at autopsy from 70 aged (33 males and 37 females) and 22 young (13 males and nine females) individuals. The liver iron stores of young males (327.00 +/- 50.57 micrograms/g) (mean +/- SEM) are higher than young females (143.48 +/- 32.94 micrograms/g; P < 0.02). There is no difference between the values found for old males (301.72 +/- 31.70 microgram/g) and old females (258.61 +/- 24.14 micrograms/g) or between young and old males. The incidence of low iron stores (less than 50 microgram/g) in males and females of the aged group is similar to that found in the group of young males. It is concluded that in the aged Spanish population studied iron stores are not diminished.

Adult↗
PubMed1979

Reduced leucocyte alkaline phosphatase activity and decreased NBT reduction test in induced iron deficiency anaemia in rabbits.

Iron deficiency anaemia was induced in rabbits by repeated bleeding. The leucocyte alkaline phosphatase (LAP) of 26 +/- 28 units was significantly reduced compared with control values of 233 +/- 35 units (P less than 0.001). Leucocyte NBT reduction was also diminished, both in Hanks solution (P less than 0.01) and in autologous serum (P less than 0.001). After administration of iron, these values returned to normal. The results suggest that reduced LAP may reflect a deficiency of iron dependent constituents which are necessary for the integrity of normal granulocyte metabolism.

Alkaline Phosphatase↗