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Biomedical subjects

V Golli

Publications and source records attributed to V Golli.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[A survey of recommended measures in COPD (II)].

The authors aimed to test the doctors' opinion-general practitioners (Gen), internal medicine specialists (Int) and pulmonologists (PNF) about the therapeutic approach in COPD. 300 questionnaires including 53 questions were mailed; 103 filled-in questionnaires were recovered (33.34%). Most of the doctors consider necessary the initial diagnosis in hospital. The Gen send the patients mostly to the Int and less to the PNF. Most doctors accept that the treatment should be started in pulmonology clinics. All the doctors prescribe teophillins; the beta-agonists are prescribed twice as much by the PNF than Int, and very little by Gen. The oral corticosteroids are used by half of the doctors; the inhaled corticoids are prescribed seldom and only by PNF. The i.v. corticoids are used by half of Int. All the doctors recommend smoking cessation. Only the PNF drag the attention upon the bacterial infections. The kinesitherapy is seldom recommended, even by PNF.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Current incidence of the aged among hospitalized tuberculosis patients].

A survey including 10 442 tuberculosis patients hospitalized in a sanatorium showed that 1 086 (10.42%) were 65 years old or older, the proportion increasing from 5.21% in 1964 to 12.78% in 1973 (p less than 0.001). The patients over 70 represented 3.73% of the total, increasing twofold in the course of ten years, from 2.37% to 4.15% (p less than 0.05). There was a rural prevalence, i.e. 11.9% as against 6.85% from urban areas (p less than 0.001), and in the over 70 years age group 4.13% as against 2.74% (p less than 0.001).

Age Factors↗
PubMedDate not supplied

[Investigation of some risk factors in tubercular infection in children].

A total of 2057 children, from a village with an isolated farm of tuberculous cattle have been classified in the following groups: A--1843 children from healthy families; B--140 children whose parents were working at the bovine farm; C--70 tb contacts, and D--4 children with parents working at the farm and relatives suffering with tuberculosis. All were skin tested simultaneously with 1 and 10 PPD units. Milk was brought home from the farm by those who worked there, that was used without boiling. A total of 14,5% of all the children had a reaction of more than 5 mm to one PPD unit. The percentages were of 8,4 in group A 52,1 in group B and 94,3 in group C (P less than 0,001). Incidence of more than 9 mm reactions was of 5% in group A, 45% in group B and 91,4% in group C (P less than 0,001). The mean diameter for one PPD unit was of 1,1 mm in group A, 7,58 mm in group B and 15,88 mm in group C (P less than 0,001). The major risk factor is represented by the tuberculous patients, but use of milk, or of milk derivatives from diseased cattle could also be incriminated. Synchronous neutralization of these two sources of contamination remains the primary action to be carried out for the prevention of the tuberculous infection dissemination.

Adolescent↗
PubMedDate not supplied

[Current incidence of tubercular infection in children in the Dolj district].

A lot of 122459 children under the age of 14 were tested intradermally with 2 U PPD. Most of them had been vaccinated at birth and some revaccinated later during the 1966-1967 period, which does not represent interpretation of the prevalance of tuberculosis today, bearing in mind the low postvaccinal allergy of young children and the interval after the last vaccination, only the children with a reaction of more than 10 mm in diameter were taken into consideration as they represented the highest probability of the actual spread of the infection. In the age group up to 6 years 6.82% of the children were infected and 17.12% of the school children of grades II to VIII, i.e. less than the mean values recorded in the whole country. This was attributed to the intensive specific chemotherapy applied within the area. The prevalence gradually increased from 3.93% at the age of l year to 4.90% at 3 years, then sharply to 6.93% at 4 years (when the child's relations are extended) and 10.46% at 5 years. The proportion of infections was of 12--13% in grades II--IV (7-9 years), 16.63% in grade V, 20% in grade VI and 23.21% in grade VIII (13-14 years). The present values are much lower than those recorded in 1966. The present risk of infection is of 1%, with an annual decrease rate of 7%, starting in 1956. By comparison with the published data it is considered that neutralization by chemotherapy of all bacilli carriers will accelerate the rate of decrease of infection.

Adolescent↗
PubMedDate not supplied

[Current incidence and clinical significance of non-culturable bacilli or those culturable with difficulty].

An analysis of 246 patients with positive smear present bacilli and negative cultures revealed that in only 9% of the cases no organized previous treatment had been applied, although almost half of these had benefited from short courses with streptomycin associated with penicillin before an exact diagnosis of tuberculosis had been made. Since the remaining 91% had had 1--2 months of chemotherapy, which frequently included rifampicin, the authors stress that microscopically detectable germs are frequently incapable to develop on culture media. These are frequently non-viable bacteria and in such conditions no subsequent modifications of the currently applied therapy scheme should be attempted. The authors show that only 26,2% of the germs from 519 positive cultures have developed after 21 days from the seeding. At 30 days the overall proportion increased to 71,2% while at 45 days 22,7% more positive cultures appeared and an additional 6,1% cultures became positive at 60 days. Tubercle bacilli become increasingly demanding and slower growing. If at 21 days only one colony was evident in 6% of the cases, while an infinite number of colonies were present in 58% of the cultures at 60 days a single colony was found in 42% of the cases, in contrast with only 9% cases with an infinite number of colonies (P less than 0,001). The delay in the growth of bacilli was parallel with the duration of chemotherapy. The results are compared with data from the literature.

Antitubercular Agents↗
PubMedDate not supplied

[Strictly supervised antitubercular chemotherapy in district and plant medical dispensaries in the city of Craiova].

The mode of administration of chemotherapy is evaluated, in conditions of integration, and under strict supervision, in tuberculosis patients in 12 medical dispensaries and in 6 enterprise dispensaries from Craiova over a period of one year. A total of 88,54 +/- 17,99 per cent of the number of programmed doses was administered in the territorial medical dispensary, as compared with 81,9 +/- 21,3 per cent in the tuberculosis dispensary. In enterprise dispensaries 97,69 +/- 16,17 per cent of the doses was given effectively, as compared with 78,17 +/- 29,39 per cent of doses given to the same patients in the tuberculosis dispensary. During the sick-leave 92,14 +/- 9,19 per cent of the doses were given, in the medical territorial dispensary as against 86,98 +/- 17,58 per cent in the tuberculosis dispensary. The difference is not significant. After reinsertion 77,53 +/- 24,84 per cent of the programmed doses were administered in the tuberculosis dispensary, 88,2 +/- 19,84 per cent in the territorial medical dispensary and 97,12 +/- 5,66 per cent in the enterprise dispensary. The differences were not significant. The authors conclude that administration of anti-tuberculosis chemotherapy can be perfectly well carried out in integrated conditions in the urban environment, especially in interprise medical units, after reinsertion. The phtysiologist should make a periodical survey in these units in view of securing a strict administration of the treatment regimens.

Ambulatory Care Facilities↗