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Biomedical subjects

V Gheorghe

Publications and source records attributed to V Gheorghe.

12 recordsLinked to original sources

Interferometric evaluation of collagen concentration in tendon fibers.

The dry mass concentration of collagen in native rat tail tendon fibers was studied by interferometric techniques. It could be shown that the collagen concentration of rat tail tendon fibers is not constant nor does it vary uniformly with the fiber diameter. Evidence is presented that the collagen concentration shows significant oscillations as a function of diameter. In order to explain the experimental findings, a layered model is proposed for the fiber structure; age dependent changes were also studied. It seems that the fiber structure is unaltered by ageing at the supramolecular level but its functional capacities are affected and swelling is inhibited.

Age Factors

Evaluation of nutrient value and a classification of food products of animal origin in accordance with reconsidered water/protein ratio.

Water/protein ratio, criterion of evaluation of comparative nutrive value of meat products, fully used at present in some European countries, does not take into account the nutritive value of protein from the structure. This work presents a reconsideration of the evaluation of food proteinogenic value, on the basis of numerous analytical data from collagen dosing and setting of collagen/protein ratio as well as from biological tests on laboratory animals, thus correcting the amount of total protein and, implicitly, water/protein ratio. Tables of these products structure and classification in accordance with water/protein ratio are given.

Animals

Hydration forces involved in cellular interactions.

Cellular physical interactions are determinant in many and various biological processes: aggregation, adhesion, segregation, contact inhibition, fusion, etc. A real advance concerning the understanding of cellular interactions from a physical point of view has been performed of late, but a great many problems still remain to be clarified. Thus, DLVO theory extrapolated to cell-cell interactions, is unable to describe cellular interactions at very short distances of separation, where other forces play an important role. A sketch of the original form of DLVO theory, its criticism along with the nature and mechanism of the short range repulsive forces (hydration forces) are presented and discussed.

Animals