Vulvitis circumscripta plasmacellularis.
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Cyclosporine↗
Biomedical subjects
V Geti
Publications and source records attributed to V Geti.
Epidemiology of the dermatophytoses in the Florence area of Italy: 1985-1990. Trichophyton mentagrophytes, Epidermophyton floccosum and Microsporum gypseum infections.
Between 1985 and 1990 we observed 2085 cases of dermatophytoses in the Florence area of Italy. Trichophyton rubrum and Microsporum canis were the major etiological agents. 126 cases of dermatophytoses observed during this period were caused by Trichophyton mentagrophytes. Most of the patients came from rural areas or they kept pets. Epidermophyton floccosum ranked fourth in frequency (95 cases). The patients were adults and mainly males, most of whom engaged in sports or lived in group environments. Microsporum gypseum was isolated in 31 cases. Infections occurred directly from contact with soil or domestic animals. We report the principal clinical data concerning these last three dermatophyte infections.
Adult↗
[Benign symmetric lipomatosis].
Benign symmetric lipomatosis is a rare disease that predominantly affects males. A close correlation with alcohol and nicotine abuse, metabolic disturbances and malignant tumours of the upper airways has been observed. We report the case of a 61-year-old female patient whose first clinical lesions had appeared more than 30 years earlier. The huge enlargement of fatty tissue had also involved her face. Case history, laboratory findings and radiological and ultrasound examinations allowed us to exclude metabolic disturbances and associated diseases.
Adipose Tissue↗
[Heterogenicity of anti-basal membrane antibodies in pemphigoid. Research with the method of dermo-epidermal separation].
Twenty-one sera from subjects with bullous pemphigoid (BP), one from a subject with cicatricial pemphigoid (CP) and one from a subject with herpes gestationis (HG) were examined by indirect immunofluorescence with two substrata, intact normal human skin and human skin incubated in 1.O M NaC1 for 72 hours at 4 degrees C, that permit the dermal-epidermal separation at the lamina lucida layer. Eight of the 21 BP sera presented linear fluorescence in the dermal-epidermal junction of intact skin. On "separated" skin four of these eight sera showed fluorescence on the epidermal side, one on the dermal side, and one on both sides. The CP sera showed fluorescence at the dermal-epidermal junction on intact skin and on both sides on "separated" skin. The HG sera did not evidence fluorescent deposits with either of the two substrata. However, when examined by the complement fixation test, the HG sera showed linear fluorescence on the dermal-epidermal junction on intacty skin and a deposit on the epidermal side on "separated" skin.
Antibody Specificity↗
[IgA anti-endomysium antibodies in dermatitis herpetiformis: a sensitive marker of gluten enteropathy].
The paper reports the results of a preliminary study using indirect immunofluorescent methods on serum samples from 20 patients affected by dermatitis herpetiformis in various phases of development and from 7 patients affected by celiac disease in order to document the presence of anti-endomysium IgA antibodies. Serum samples from 10 patients affected by bullous pemphigoid, 1 patients with linear IgA dermatitis and 10 patients with other bullous dermatosis were included as controls. Whereas the presence of these antibodies in varying titres, ranging from 1:10 to 1:80, was confirmed in all case of dermatitis herpetiformis, no antibody activity was observed in control patients. On the basis of these findings and of other published data, it is possible to conclude that these antibodies are directly correlated to intestinal damage, but there is no relationship with the clinical characteristics of skin symptoms or with junctional immunopathological evidence.
Celiac Disease↗
[The so-called herpes gestationis factor in bullous pemphigoid].
We have investigated the presence of the so-called "herpes gestationis factor" in the serum of fifteen patients with bullous pemphigoid and one patient with cicatricial pemphigoid, that were negative for circulating anti-basement membrane antibodies, using the complement fixation test (substrate: human normal skin, 0 group). We have found herpes gestationis factor in 30% of the serologically negative patients. The presence in the serum of an auto-antibody IgG1 (HGF) highly avid for complement, may determine the false serological negativity in this patient.
Autoantibodies↗
Dermatophyte infection in ichthyosis vulgaris.
A 31-year-old male who had been suffering from ichthyosis vulgaris developed hyperkeratosic lesions on the palms and soles and ungual alterations of both hands and feet. These lesions were resistant to topical corticosteroid and emollient cream treatments and were found to be caused by Trichophyton rubrum. Association of ichthyosis vulgaris and dermatophytosis--both very common disorders--is to our knowledge a very rare event.
Adult↗