Search PubMed⌕ Search

Biomedical subjects

V Garrigues Gil

Publications and source records attributed to V Garrigues Gil.

10 recordsLinked to original sources

[Approach to thoracic pain from the gastroenterologist's point of view].

Chest pain is common in medical consultations. One of the most frequent and serious causes is acute ischemic heart disease, which must be ruled out. The gold standard is coronary angiography. Noncardiac recurrent chest pain has a favorable prognosis. The most frequent cause is esophageal disease, with a prevalence of between 20% and 50%. The most frequent form is gastroesophageal reflux disease followed by esophageal motor disorders. Empirical treatment with high-dose proton pump inhibitors should be considered as a diagnostic-therapeutic test before performing exhaustive complementary investigations of esophageal function. Among complementary tests, manometry combined with 24-hour pH-metry has the highest diagnostic yield. Antidepressants are an acceptable therapeutic option in patients with esophageal visceral hyperalgesia.

Chest Pain↗

[Chronic cough].

Explore the source record for details and available documents.

Adult↗

[Esophageal achalasia with apparently normal relaxation of the lower sphincter: clinical significance and therapeutic response to pneumatic dilatation].

OBJECTIVE: To evaluate if the clinical presentation and the response to pneumatic dilation is different in patients with achalasia with an apparent normal lower esophageal sphincter relaxation. DESIGN: Prospective study to compare clinical, radiographic and manometric characteristics and the response to pneumatic dilation according to the ability of the lower esophageal sphincter to relax normally. PATIENTS: One hundred and fifty seven consecutive patients with achalasia were included. Relaxation of the lower esophageal sphincter was abnormal in 130 patients and apparently normal in 27. The response to pneumatic dilation was evaluated in 116 patients, 94 with abnormal function of the lower esophageal sphincter and 22 with normal function. RESULTS: Clinical findings, esophageal diameter and basal pressure of the lower esophageal sphincter were similar in both groups. The efficacy of the dilation, the number of dilations and the rate of complications were also similar. CONCLUSIONS: Patients with achalasia and an apparent normal lower esophageal sphincter relaxation are not different from patients with typical achalasia and present a similar response to pneumatic dilation.

Adult↗

[Computer-assisted analysis of the prognosis in patients with upper gastrointestinal hemorrhage].

The prognosis of 189 patients with upper gastrointestinal bleeding was studied with the assistance of a computer. The safety of the prognosis given by the doctor was partially improved with the computer. However, when both judgements were simultaneously considered, the best results were obtained. A scoring-system constructed with simple clinical data proved useful to obtain prognostic judgements with high sensitivity and specificity. It is concluded that the reliability of the prognosis given in patients with upper gastrointestinal bleeding can be improved with objective methods. The improvement is maximal if objective information is evaluated together with clinical information.

Adult↗

[Are there clinical differences between typical and vigorous achalasia and response to pneumatic dilatation?].

The aim of this study was to analyze whether the vigorous character of esophageal contraction conditions differences in the clinical characteristics or in response to pneumatic dilatation treatment in patients with achalasia. To do so, a prospective protocol study was designed in which the clinical, radiological, and manometric characteristics of the patients and the response to pneumatic dilatation were compared on the basis of the presence or absence of severe contraction of the esophageal body. One hundred fifty-seven consecutive patients diagnosed with achalasia were included on presentation of a compatible clinical picture and absence of peristalsis in the esophageal body. Out of these patients, 120 presented a manometric pattern of typical achalasia and 37 had vigorous achalasia. Response to pneumatic dilatation was analyzed in 116 patients, 90 with typical achalasia and 26 with vigorous achalasia. Significant differences were only found between the two groups with respect to the greater response tone of the lower esophageal sphincter observed in the patients with vigorous achalasia. There were no differences in the remaining clinical, radiologic or manometric variables compared. Neither were any differences observed in regard to therapeutic response to pneumatic dilatation in the two groups of patients. It may be concluded that differentiation between typical and vigorous achalasia has no clinical or therapeutic significance.

Adolescent↗