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Biomedical subjects

V G Novozhenov

Publications and source records attributed to V G Novozhenov.

At least 37 records · Page 2Linked to original sources
PubMed2000

[The medical rehabilitation of servicemen following aortocoronary bypass].

The results of aortocoronary shunting (ACSh) were studied in 243 patients after myocardial infarction at different stages of rehabilitation--in rehabilitative hospital and military sanatorium. Result assessment at the final stage of therapy in sanatorium confirmed ACSh efficiency in overwhelming majority of patients. At the same time principal peculiarities were revealed showing the necessity of differential approach to determination of volume and place for conduction of restorative therapy. Process of successful adaptation in most patients is achieved during the periods up to 8 weeks that corresponds to two-staged rehabilitative system. More long periods of therapy are required for patients having complications not arrested at hospital stage, low exercise tolerance, poor psychological readaptation. Optimization of rehabilitative system in order to determine the volume and place of rehabilitation will contribute to further improvement of staged therapy in such patient group.

Adaptation, Psychological↗
PubMed1996

[Chronic obstructive bronchitis: its pathogenetic aspects and the characteristics of its clinical course].

Lipid peroxidation (LPO) and antioxidant system (AOS) were examined in 40 inpatients with chronic obstructive bronchitis (COB) on conventional treatment. The above parameters were considered in relation to clinical picture. It is shown that inflammation in the bronchial tree is associated with AOS functional deterioration and marked LPO intensification. A correlation was established between LPO activity, concentration of alpha-tocopherol in red cell membrane and degree of bronchial obstruction as well as remission quality. Persistent high intensity of LPO is suggested as an underlying cause of the disease transition to chronic form and progression of bronchial obstruction. Basing on the above observations, the authors insist on antioxidants introduction in COB treatment.

Adolescent↗
PubMed1996

[Pulmonary complications in severe combined craniocerebral trauma (their pathogenesis, clinical picture, diagnosis and treatment)].

Within 1979-1989 the authors treated 26 wounded soldiers and officers with brain injury inflicted by mine explosion. 5 patients were in severe condition, 18 in extremely grave and 3 in critical condition. The patients had concomitant blast injuries and contusions. Pulmonary complications observed in such patients compused to DIC and respiratory distress syndromes running in the presence of marked metabolic disorders, hypoxia and intoxication. It is thought important that conservative therapy of respiratory disorders in patients with brain traumas were not constricted with correction of bronchial obstruction. The additional intensive treatment of the above syndromes is needed including extracorporeal detoxication (plasmapheresis) and hyperbaric oxygenation.

Acute Disease↗
PubMed1995

[Current problems in organizing therapeutic care].

The article studies the problems in organization of therapeutical care in Mobile Forces on the basis of the analysis of medical support of troops in local wars. The authors emphasize the high dynamics of changes in the structure of military disease hazards depending on different combat theaters. This fact proves the necessity to make a transition to a module principle of formation of medical units and establishments which provide medical care to the wounded and sick.

Delivery of Health Care↗
PubMed1995

[The pathogenesis of a broncho-obstructive syndrome in patients with chronic bronchitis].

Lipid peroxidation (LPO) and antioxidant system (AOS) were investigated in 40 patients with chronic obstructive bronchitis (COB) in relation to clinical features of the disease. Bronchial tree inflammation was associated with reduced AOS function and intensification of LPO which reached a new high level. LPO activity, tocopherol concentration in red cell membranes and the severity of respiratory obstructive syndrome were correlated. It is suggested that high LPO activity may underlie the disease chronicity and development of progressive irreversible bronchial obstruction. Antioxidant drugs are believed necessary for COB patients not only in acute, but also in regression and remission phases of the disease.

Adolescent↗
PubMed1994

[The clinical course of acute pneumonia in servicemen in Afghanistan].

The study of 820 histories was carried out in order to ascertain characteristic features of clinical course of acute pneumonia in the conditions of Afghanistan. All these patients underwent treatment in the Central Military Hospital of the 40th Army in Kabul in 1980-1989. The immunity status, the the level of peroxide oxidation of lipids (POL), and the state of antioxidant system (AOS) were also studied in 132 patients. The clinical course of pneumonia in comparison with its manifestation on the territory of Russia was characterized by pronounced intoxication of an organism, broncho-obstruction, vast inflammatory infiltration, hyperactivization of the immune system, POL, and AOS exhaustion. All these factors correspond to the syndrome of disadoptative disorders. Medications recommended for complex treatment: antioxidants, immunoglobulins, albumin, low-molecular dextrans.

Acute Disease↗