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Biomedical subjects

V G Levchenko

Publications and source records attributed to V G Levchenko.

4 recordsLinked to original sources

[The prediction of the probability of the development of myocardial infarct by genetic and phenotypic markers].

The study was made of marker distribution of 17 hereditary polymorphism systems in 493 patients with myocardial infarction (MI) and 422 healthy subjects. The prognostic system for determination of predisposition or resistance to MI development has been designed in accordance with marker occurrence in the patients and healthy subjects basing on Bayer's method. When the sum of the prognostic ratios of all the markers is +5 scores and more there is a high risk of MI, when this sum is -6 scores and less the resistance to its genesis is predicted. The proposed prognostic system makes it possible to predict predisposition to myocardial infarction at an early age and, therefore, to take preventive measures.

Adult↗

[Experience with conducting programmed labor].

An analysis was made of programmed labours in 128 high-risk females having relative indications for cesarean section. Oxytocin or prostaglandin was used as a uterine-contracting agents. The dosage, rate and duration of drug administration were adjusted by the values of uterine activity and the rate of cervical dilatation. In the latent phase (up to 4-5 cm) the optimal dilatation rate was considered to be 1 cm/h in primiparas, 1.5 cm/h in multiparas; in the active period (over 5 cm), that was 1.5 and 2.0 cm/h, respectively. The optimal labour duration was at least 10-12 hours in primiparas and at least 8 hours in multiparas. One hundred and sixteen (90.6%) females delivered vaginally without any delivery operations. Twelve (9.4%) delivered via cesarean section. All 128 babies were liveborn. It has been concluded that programmed labour is a sparing tool of delivery in high-risk pregnant who have no indications for cesarean section.

Abortion, Induced↗