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Biomedical subjects

V G Goriunov

Publications and source records attributed to V G Goriunov.

At least 19 recordsLinked to original sources

[The results of prostatic adenomectomy in patients with severe concomitant diseases].

Immediate and long-term results of prostate adenomectomy were studied in 1549 patients, 322 of whom being of old age. In 1499 (96.8%) patients concomitant diseases were revealed: ischemic heart disease (934 patients), cardiosclerosis after 1-3 myocardial infarction (185), hemiparesis after acute cerebrovascular disturbances (74), diabetes mellitus (88), chronic lymphoid leukemia (5), cirrhosis of the liver (15), cancer (22) and true diverticula (15) of the urine bladder, drug-related polyallergy (16). 628 patients were radically operated in conditions of circulatory insufficiency of stage I-II. In 631 (40.7%) patients surgical intervention was carried out as urgent because of acute dysuria (hampering of urination) or to bleeding from tumor. Transvesical adenomectomy was carried out with hemostasis by 2 semipouch string removable sutures. In 89.5% of patients uncomplicated course of postoperative period was observed. Postoperative lethality in patients with concomitant diseases made up 3.2%. Causes of death were postinfarction cardiosclerosis (6.5%), after-effect of cerebrovascular stroke (5.4%), diabetes mellitus (5.7%), cirrhosis of the liver (6.7%). 6 months to 11 years after the operation 91.2% of the patients achieved good follow-up functional results of surgical treatment, in majority of the patients medical and social rehabilitation was observed.

Aged↗

[An experimental validation of organ-preserving operations in traumatic lesions of the parenchymatous organs].

Resulting from the experiment performed on 32 dogs, the authors have established that the use of technology of tissue bioinhibition and cryogenic influence led to local cryopreservation, hypercoagulation and change in the physical properties of the damaged parenchyma. This contributes to successful performance of the organ preserving operations and prevents the development of early and long-term postoperative complications.

Animals↗

[Intratesticular stimulation of spermatogenesis].

The possibility to exert local effect on suppressed spermatogenesis in patients with different forms of secretory sterility is presented. To this end, the authors created an experimental model of 10-minute acute ischemia in mouse testis. Destructive changes in the testicular parenchyma after the 3., 9., 22. and 30 day were observed and described. Testosterone concentration in the tissues of the ischemic and the contralateral testis was determined by highly effective liquid chromatography. It is concluded that saturation of the interstitium with androgens may avert irreversible postischemic sequelae in the testis. At first chorion gonadotropin and testosterone, but later on Sustanon-250 with prolonged action, were used as protectors. This experimental study is a contribution both to the investigation of spermatogenesis physiology and disturbances and to the refinement of the treatment of secretory forms of male sterility.

Animals↗

[The role of a sanatorium-health resort factor in the complex treatment of patients with chronic prostatitis].

The results of two-step treatment of 62 patients with chronic prostatitis are presented. The first-step treatment was given at the clinic of the Urologic Research Institute of the RSFSR Ministry of Health, and the second step was completed at the Zheleznovodsk Urologic Clinic of the Pyatigorsk Research Institute of Health Resort Treatment and Physiotherapy. In addition to its medical aspect, treatment for chronic prostatitis has significant social implications, as chronic prostatitis mostly affects males of young or middle age, with the inflammation persisting for long periods of time and leading to sexual and reproductive disorders as well as psychoneuroses. Since chronic prostatitis is regarded as an inflammatory disease of infectious-immunologic etiology, with both parenchymal and interstitial tissues of the prostatic gland affected, the patients underwent antibacterial treatment, adjusted to the causative agent's sensitivity to antibacterial drugs, and the availability of physiotherapeutic procedures in hospital as the first stage of treatment. Those to whom further rehabilitation was indicated were referred to the Zheleznovodsc Urologic Clinic where they were given a treatment course making use of the natural factors: oral and external administration of mineral waters of the Smirnovsky and Slavyanovsky springs, mud treatments and physiotherapy where indicated. Treatment was designed to improve microcirculation in prostatic tissues, and used natural factors, capable of normalizing and activating systemic protective potentials. There were good results (considerably improved general condition, both subjectively felt and objectively documented) in 78%.(ABSTRACT TRUNCATED AT 250 WORDS)

Chronic Disease↗

[Transient obstructive aspermia and transient obstructive oligospermia].

The article is a continuation of a series of papers dealing with changes of ejaculatory ducts associated with various diseases of the prostatic gland and posterior urethra. Clinical description of patients, earlier treated for aspermia or oligospermia is presented. In some of the patients with such clinical manifestations, complete or partial compression of the ejaculatory ducts by the inflamed prostate or seminal bulb may be the cause and the disorder may be transitory rather than continuous. Twenty-six cases of transitory aspermia are reported, with special reference to laboratory and instrumental findings and treatment results. A group of patients (43) with transitory oligospermia is also described, and the results of investigation and treatment are presented.

Adult↗