Thirty-four patients with ischemic heart disease (IHD) were studied: 18 IHD patients with latent forms of disturbances of conductivity in the atrioventricular junction and sinus node sickness syndrome revealed at frequency stimulation of the heart; 16 patients with acute myocardial infarction complicated with the atrioventricular junction blockade of II and III degrees. Ildamen solution (4 mg) was slowly intravenously infused to all patients under study. Exerting the beta-stimulating effect, ildamen positively influences restoration of the disordered function of the pacemaker and conduction system of the heart: through immediate action on these systems and an increase of the coronary blood flow contributing to improvement of nutrition of the condition system of the heart.

Adrenergic beta-Agonists↗

PubMedDate not supplied

[Comparative evaluation of the cardiotropic effect of broncholytic agents].

The cardiotropic effect of broncholytic agents of different groups used for treatment of bronchial asthma was analyzed by using the method of determination of isoenzyme of MB creatine phosphokinase (CPK) and total CPK in the blood of the patients. A total of 125 biochemical assays on determination of CPK in the blood of the patients were made. The cardiotropic effects of three agents (adrenaline, novodrin, Berodual) were studied. Adrenomimetics adrenaline and isodrin (novodrin) were shown to increase significantly CPK activity. A combined agent Berodual insignificantly increased the activity of MB isoenzyme of CPK.

Asthma↗

PubMedDate not supplied

[Nitroglycerin pharmacodynamics in myocardial infarct].

The experience of treating 2,500 patients with acute myocardial infarction enabled the authors to prove a diverse character of nitroglycerin effect: it exerts a positive inotropic action on the myocardium, improves elastic properties of the myocardium, normalizes energy balance of the myocardium, influences the system of the blood aggregate state through contractile elements of platelets producing a hypocoagulatory effect.

Cardiovascular System↗

PubMedDate not supplied

[Thyroid state and thyrotropic function of the pituitary gland in sportsmen during veloergometric exercise].

The total and aerobic productivity, the content of the thyroid hormones, thyrotropin, lactate, and acid-base balance in the blood of 52 highly skilled sportsmen were studied in the process of veloergometric exercises of different intensity. It was shown that thyroxin and thyrotropin content increased and triiodothyronine concentration decreased in the blood plasma under the action of veloergometric exercises. A rise in cell metabolism and changes in the internal medium of the organism influence the alteration of the blood thyroid hormone and thyrotropin levels. Thyroid and hypophyseal thyrotropic functions depend to a certain degree on the exercise intensity and functional preparedness of the sportsmen.

Adolescent↗