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Biomedical subjects

V Forte

Publications and source records attributed to V Forte.

71 records · Page 4Linked to original sources

The evaluation of intranasal topical beclomethasone spray in the treatment of children with non-purulent rhinitis using rhinometric, cytologic and symptomatologic assessment.

The diagnosis and treatment of non-purulent rhinitis in the pediatric population poses a challenge to the clinician. In this randomized double blind study, the authors conclude that rhinometry is more effective than cytologic or symptomologic assessment in children with non-purulent rhinitis treated with either intranasal beclomethasone or placebo spray. Intranasal beclomethasone spray produced significant reductions in nasal airflow resistance values compared to the placebo-treated group.

Administration, Intranasal↗

Objective tinnitus associated with abnormal mastoid emissary vein.

Tinnitus may be defined as the perception of sound in the absence of environmental input. It can be subjective. Objective tinnitus may be caused by clearly definable mechanical or vascular abnormalities, and as such may be amenable to specific management. We report a case of objective tinnitus associated with an abnormal mastoid emissary vein. A review of the literature identified only one other report of objective tinnitus associated with an emissary vein. That report involved a posterior condylar emissary vein. The venous drainage of the sigmoid sinus was studied on 50 human skulls demonstrating three possible emissary veins of each sigmoid sinus. The postauricular region was dopplered on 30 asymptomatic human subjects. None was found to have dopplered emissary vein flow.

Adolescent↗

Maximal cardiorespiratory responses to one- and two-legged cycling during acute and long-term exposure to 4300 meters altitude.

During exposure to altitudes greater than about 2200 m, maximal oxygen uptake (VO2max) is immediately diminished in proportion to the reduction in the partial pressure of oxygen in the inspired air. If the exposure lasts longer than a couple of days, an increase in arterial oxygen content (CaO2), due to a hemoconcentration and an increase in arterial oxygen saturation, occurs. However, there is also a reduction in maximal cardiac output (Qmax) at altitude which offsets the increase in CaO2 and, therefore, VO2max does not improve. The purpose of this investigation was to study the contribution of the increase in CaO2 to the working muscles without the potentially confounding problem of a reduced Qmax. The approach used was to have seven male subjects (aged 17 to 24 years) perform one- and two-legged VO2max tests on a cycle ergometer at sea level (SL, PIO2 = 159 Torr), after 1 h at 4300 m simulated altitude (SA, PIO2 = 94 Torr) and during two weeks of residence on the summit of Pikes Peak, CO. (PP, 4300 m, PIO2 = 94 Torr). Cardiac output limits maximal performance during two-legged cycling but does not limit performance during one-legged cycling. During the study, CaO2 changed from 189 +/- 3 (mean +/- SE) at SL to 161 +/- 4 ml.L-1 during SA (SL vs. SA, p less than 0.01) and to 200 +/- 6 ml.L-1 at PP (SL vs. PP, p less than 0.05; SA vs. PP, p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Acquired bronchial injury in neonates.

The increasing success of modern neonatology has been associated with the use of prolonged intubation, ventilation and respiratory support. Inappropriate management of the endotrachial tubes or excessive and improper use of suction catheters may result in significant tracheobronchial injury. These injuries range from readily reversible abrasions through to obstructing granulomas, polyps and even bronchial stenosis and acquired bronchial atresia. These lesions are for the most part preventable with appropriate patient care. Examples of these lesions are presented.

Bronchi↗

Posterior tracheal wall disruption: a rare complication of pediatric tracheotomy and bronchoscopy.

Disruption of the posterior tracheal wall is an uncommon complication of tracheotomy, bronchoscopy, or even endotracheal intubation. With disruption of the posterior tracheal wall, air tracking may present as surgical emphysema, pneumomediastinum, or pneumothoraces, and may be associated with respiratory distress. Six children with posterior tracheal wall disruptions are presented: three associated with tracheotomy, one bronchoscopy, and another during endotracheal intubation. Early recognition and appropriate management of tracheal disruption will minimize air tracking and the associated morbidity. Tracheal disruption may be avoided by utilizing appropriate surgical, endoscopic, and intubation techniques.

Adolescent↗

Objective assessment of upper airway resistance in the tracheotomized patient.

A test has been devised for measuring upper airway resistance to respiratory airflow in the tracheotomized patient. The test is simple and noninvasive; it utilizes either a body plethysmograph or an oral pneumotach to measure airflow. Pressure is measured through the tracheostomy tube of the stoma below the partial obstruction of the upper airway. The test has many important clinical applications. Its technique, rationale for use, and some clinical applications are briefly discussed in this paper, together with basic concepts of flow dynamics.

Airway Obstruction↗

Expansion of myocutaneous flaps.

The controlled expansion of myocutaneous flaps offers a potential means of increasing their size. The pectoralis major flap was successfully expanded in pigs, giving mean percentage increases in the axial lengths of 32% and widths of 51% over nonexpanded controls. Angiographic and histomorphologic studies of the expanded flaps demonstrated the vascular and histologic changes that resulted. This new surgical technique should prove valuable in extending the field of head and neck reconstruction in man.

Angiography↗

Nose/mouth distribution of respiratory airflow in 'mouth breathing' children.

Oro-nasal distribution of respiratory airflow was determined in 120 'mouth breathing' children by a minimally invasive computer-assisted method that employed a modified CPAP nasal mask/pneumotach and a head-out body plethysmograph. Resulting measurements were reproducible but clinical assessments correlated poorly with these values. Airflow distribution was almost identical in inspiration and expiration. 100% nasal breathing was found over a wide range of nasal resistances, many subjects with lips apart. Overall, the nasal fraction was negatively correlated with resistance and it was increased by topical decongestant. Decreasing nasal resistance with increasing age was confirmed, but corresponding changes in airflow distribution were not demonstrated. Quantitative assessment is advocated in clinical management of 'mouth breathers'.

Airway Resistance↗