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Biomedical subjects

V Fabecić-Sabadi

Publications and source records attributed to V Fabecić-Sabadi.

18 recordsLinked to original sources
PubMed1998

[The effect of prevention and other factors in the decrease in rheumatic fever].

933 children with rheumatic fever hospitalised in Clinic in the period of 40 years (from 1995 to the end of 1994) were analysed in order to establish the fluctuation of patients number and changes in clinical appearance. Patients were divided in 4 groups: I. the patients hospitalised from 1955-1964 (472 patients), II. from 1965-1974 (307), III. from 1975-1984 (135), IV. from 1985-1994 (19). The data for Republic Croatia show the steady fall of the number of hospitalised children with rheumatic fever. Carditis with polyarthritis were present in the largest part of our patients (446 namely 47.8%). The number of recurrences fell equally with the number of patients with rheumatic fever. However, ratio between the number of patients with rheumatic fever and the number of recurrences did not change essentially, that was 11-15.85% in the periods considered. The percent of hospitalised children with fixed rheumatic heart disease was 4.23% in the I. period to as much as 15.5% in the III. period from totally hospitalised children with rheumatic fever. In the last time the disease became mild in its development. All children with suspicion on rheumatic fever should be hospitalised. The prophylaxis, primary or secondary, should be carried out intramusculary with benzithine penicillin G, as proved as the best, in order to ensure that the child virtually received the prophylaxis.

Adolescent↗
PubMed1986

Echocardiographic findings in children participating in swimming training.

In 72 children having a body surface area from 0.8 to 1.6 m2 who systematically trained in swimming at last for 1 year, or an average of 29.2 months, echocardiographic recordings were done to find out which changes result from systematic training. The results obtained were compared with values obtained in 72 normal children, having the same body area, but who did not actively engage in sports. The measurements and analyses showed that values of the left ventricular interior diameter (LVID), left atrium (LA), and heart depth (DS) were statistically significantly increased. The values of septum thickness (SE) and left ventricular posterior wall (LVPW) were a bit larger, but statistically not significant. Contractibility of the myocardium was also examined by measurement of the ejection fraction (EF), percentage of the shortening of the left ventricle (%FS), and average velocity of the circumferential shortening of the muscular fibers (VCF). The values obtained were within limits of normal values. Results of the analysis of the influence of sports training on echocardiographic dimensions indicated four positive correlations: left ventricular interior diameter in systole (LVIDs) and diastole (LVIDd), diameter of the left atrium (LA), and heart depth (DS). In recording echocardiograms in children, it is necessary to establish whether the child actively engages in sports beforehand since long-term training leads to changes of some heart structures, which may, if it is not known that the child is active in sports, lead to wrong conclusions that the finding is pathological.

Adolescent↗
PubMed1984

Interrenal coarctation of the abdominal aorta.

We report a case of congenital, segmental, hypoplastic interrenal abdominal aortic coarctation with inadequate collateral circulation. After preoperatively evaluating renal function and intraoperatively measuring vascular pressure, the coarctation was bridged with an aortico-aorta bypass; and an additional bypass graft was placed between the prosthesis and superior mesenteric artery. In this way, besides the successful surgical correction of coarctation, the inverse blood flow in the superior mesenteric artery was reversed to normal.

Journal Article↗
PubMed1978

Hyperglycinuria with nephrolithiasis.

The case of a seven and a half-year-old girl with hyperglycinuria, oxalate nephrolithiasis, and a normal plasma amino acid pattern is presented. Hyperglycinuria amounted to 400 mg of glycine in 24 h urine and the stone was composed of calcium oxalate dihydrate. The metabolic relationship between glycine and oxalate is discussed. It is possible that the association of nephrolithiasis and hyperglycinuria was coincidental, although the case of familial hyperglycinuria with nephrolithiasis reported by De Vries and collaborators and our case suggest the possibility of a relationship between the aforesaid compounds in vivo.

Child↗
PubMedDate not supplied

[Blood pressure in neonates measured by Doppler ultrasound].

In order to provide correct care for newborns it is necessary to determine the arterial pressure, since it is an important physiological indicator of body vitality. We measured blood pressure in 50 healthy, full term infants, born in Zagreb. All blood pressure readings were done by using a Doppler ultrasound. The 4 cm width cuff was used. The mean systolic pressure was 78.76 mmHg (SD +/- 8.6) and the diastolic one 35.78 mmHg (SD +/- 6). The level of systolic pressure was associated with body-mass (r = 0.371; p < 0.01), while sex had no effect on it.

Blood Pressure↗
PubMedDate not supplied

[Aortico-left ventricular tunnel].

The boy was first admitted to the Department of Pediatric Cardiology at the age of 4 1/2 because of cardiac murmur diagnosed on the third day of life. A diastolic murmur of a grade 4/6, left ventricular hypertrophy as well as left aortal and ventricular dilatation were discovered. The findings showed a tendency of increase with time, but the patient had no symptoms. X-ray in the long axis view revealed a defect within the upper part of the interventricular septum immediately below the aorta, and dilated right coronary sinus. An invasive diagnostic method was undertaken, as well. The operative procedure was done with a total cardio-pulmonary bypass and hypothermia (29 degrees C). A tunnel from the anterior aortal wall through the outflow tract of the right ventricle to the left side of the heart was established intraoperatively. The defect was solved by a "sandwich" technique (two patch technique). Postoperative period was uneventful. A Doppler echocardiogram demonstrated the normal hemodynamic status of the patient without the left-to-right or right-to-left shunt and aortal insufficiency.

Aorta↗
PubMedDate not supplied

[Evaluation of the size of the left-right shunt using pulse Doppler echocardiography in children--personal experience].

The purpose of the present study was to verify the value of a two-dimensional pulsed Doppler echocardiographic method for measurement of pulmonary (QP) and systemic blood flow (QS) in comparison with the radiocardiography in patients with ventricular and atrial septal defects. We reviewed 42 children with ventricular septal defect and 23 children with atrial septal defect. Two-dimensional echocardiography was employed to measure the diameter of the aorta and pulmonary artery and pulsed Doppler for measurement of pulmonary and systemic blood flow velocity in the pulmonary artery and left ventricular outflow tract. By comparing pulmonary and systemic blood flow ratios by pulsed Doppler echocardiography and radiocardiography, the correlation coefficient for children with atrial septal defect and those with ventricular septal defect respectively amounted to r = 0.71 and r = 0.81. The authors conclude that two-dimensional pulsed Doppler echocardiography, although a semiquantitative technique, appears to be a reliable non-invasive method for measuring pulmonary and systemic blood flow in patients with left-to-right sgunt.

Adolescent↗
PubMedDate not supplied

[Problems in adolescents and adults with congenital heart defects].

The first palliative operations of congenital heart disease in the 1940s and 1950s, and then open heart surgery in the 1960s, have resulted in survival of patients whose follow-up is now over 30 years. Problems of patients with congenital heart disease are cardiac (pulmonary hypertension, systemic hypertension, dysrhythmias, endocarditis, cerebral insults, etc.), and noncardiac (scoliosis, intrathoracic adhesions, cosmetic problems, pregnancy, physical activity, employment, etc.). A pediatric cardiologist usually follows up such patients until adolescence, however, after that time they remain without physician's care who followed them in their childhood, being transferred for further controls and follow-up to internists-cardiologists. Many difficulties arise since internists-cardiologists are not properly trained in this particular sense, and pediatricians are not trained to follow-up adult patients. The care for a patient should be coordinated. To care for an adolescent, who was the child with congenital heart disease, pediatrician and cardiologist have to work at the same medical centre. The follow-up should continue as a team work, in which, besides pediatrician and cardiologists, cardiosurgeon, psychologist, psychiatrist, obstetrician, specialist for physical medicine and social worker should be included. A correction of educational plan is mandatory.

Adolescent↗