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Biomedical subjects

V Földes

Publications and source records attributed to V Földes.

At least 19 recordsLinked to original sources
PubMed1989

Effect of interesterified fat mixtures on certain lipid indices in experimental fat metabolism disturbance.

Groups of adult Wistar male and female rats were fed isoenergetically for a three and a six weeks period either with synthetic lipogenic diet containing 5% and 20% fat mixtures (in which sunflower oil and lard were blended according to the ratio of 35:65) or with the same synthetic diet containing the mixture of sunflower oil and interesterified lard in a similar ratio. A control group received a normal diet for 6 weeks, whereas one of the experimental groups (fed with the 20% fat mixture in the lipogenic diet for 6 weeks) was given the normal diet for an additional two weeks period. After the feeding periods had been completed serum HDL-C levels and the total lipid, triglyceride, total cholesterol, free fatty acid levels were determined in serum and liver. The distribution of fatty acids in liver and heart muscle was also evaluated. In comparison to the control values it has been found: 1. Consumption of the lipogenic diet which is known to increase the serum total lipid and total cholesterol content induced in male rats a smaller augmentation in these indices when consuming the 20% fat mixture with a P/S ratio approaching the ideal 1 values, than in case of a 5% fat mixture consumption. In case of female rats, considerable increases of the serum values, could be observed at both fat consumption levels. The serum triglyceride and HDL-C contents decreased for all experimental groups. 2. The total lipid and triglyceride content of the liver increased in a high degree, the fatty liver syndrome was developed--more rapidly in males than in females. The total lipid, triglyceride and total cholesterol contents of the liver of male rats exceeded those of females by 15-30%. 3. The interesterification of the lard component of fat mixture resulted in lipid indices similar to those without interesterification, or in certain cases, they were found to be even slightly more favourable, i.e. the biological effect of the technological change proved to be adequate. 4. After a two weeks regeneration period the serum values of the male rats approached closer the normal control values than those of the females which were decreasing from a very high level but the degree of decrease was greater for them than for the male rats. The lipid content of the liver showed similar values.(ABSTRACT TRUNCATED AT 400 WORDS)

Animals↗
PubMed1987

[Vital reactions in Pacchioni granulations].

By means of histological methods the authors examined the blood and fluid circulatory disturbances associated with cranial and cerebral injuries. The presence of vital reactions was studied by means of the combined histological study of the dura mater, pacchionian granulations and the central nervous system. Samples for histological study were taken from 115 cadavers who had suffered cranial injuries, from 15 individuals who died from destructive cerebral apoplexy caused by a disease and from 30 individuals who died of natural causes. The authors applied a special fixation and sampling technique and, using various histological reactions, the following vital reactions were observed: the appearance of blood-cell elements in the granulation, a moderate fibrin degradation product and hemoglobin phagocytosis, and occasionally lipid phagocytosis. The authors worked out a method that was shown to be highly effective in the more precise determination of the induction time of cerebral apoplexy caused by a disease and that of traumatic injury of the brain.

Brain↗
PubMed1986

[Effect of influenza virus infection on arachidonic acid cascade in mouse thrombocytes].

Prostaglandins (PGs) are essential for many physiological and pathological processes. As they are not stored in tissue, their presence and actions therefore result from de novo synthesis and release. Although platelets themselves appear to have the ability to synthesize TxA2, PGD2, arachidonic acid may also be metabolized in the lipoxygenase pathway in platelets, producing 12-hydroperoxy/12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HPETE/12-HETE). CFLP mice were infected intranasally with A/H3N2/Hong Kong (1/68) influenza virus. Platelets were isolated from the control (saline treated) and infected mice 3-13 days after virus application. Platelets were isolated from the diluted arterial blood of the mice. Metabolites of arachidonate cascade were determined using 1-14C-arachidonic acid (2035 MBq/mM spec. act.) as substrate. All incubations were carried out in TC Medium 199 (pH 7.4) at 37 degrees C for 10 min. Radiolabelled products were separated and quantitatively determined. The synthesis of TxA2 in the platelets of animals was found to be significantly increased 7 days after the virus infection. The 12-hydroxy-heptadecatrienoic acid level was higher on the 10th and 13th days of infection, as were the products of the lipoxygenase pathway.

Animals↗
PubMed1982

[Population-genetic examination of the glyoxalase I (GLO) red-cell isoenzyme system in the inhabitants of Szeged and its environment (South-Hungary) (author's transl)].

The authors have examined the gene frequency and phenotype distribution of GLO isoenzyme system in the blood samples from 1,288 randomized, unrelated persons and from 151 mother-child pairs by horizontal starch-gel electrophoresis. The observed gene frequencies (GLO1 = 0.3990, GLO2 = 0.6009) and phenotype distributions (GLO 1 = 18.1%; GLO 2-1 = 43.79%; GLO 2 = 38.20%) were in good accordance with that of the Caucasian population. The authors did not find any difference from the genetic model of two codominant alleles at an autosomal locus. The theoretical exclusion rate in paternity cases based on the GLO gene frequencies is 18.23%.

Adult↗
PubMed1981

[Population genetic examination of the esterase D (EsD) erythrocyte isoenzyme system in the inhabitants of Szeged and its environment (South Hungary) (author's transl)].

The authors have examined 1,480 random and unrelated persons who belonged to South Hungarian (Szeged and its environment) population and 159 mother-child pairs by starch-gel electrophoresis to determine the distribution of EsD enzyme polymorphism. The distribution of phenotype was as follows: EsD 1-1 = 80.74%, EsD 2-1 = 11.97%, EsD 2-2 = 1.28%. The gene-frequency values were: EsD1 = 0.8973 and EsD2 = 0.1027. The observed values do not differ significantly from the mean values of the Central European populations. The results of the examinations on mother-child pairs confirmed the established formal genetic theory of the inheritance of EsD enzyme polymorphism.

Adult↗
PubMed1980

[The measurement of testosterone content of blood stains for the criminalistic determination of sex (author's transl)].

The authors have examined the testosterone content of the blood samples from 32 women and 24 men by a radio-immunoassay technique in order to prove the method to be suitable to determine the sex from blood stains in criminalistical investigations or not. Based on the analysis of the results the testosterone determination can reliably be used to decide whether the blood stain was of female or male origin if the concentration is referred to the protein content.

Blood Stains↗
PubMed1977

[Unusual cases of maternal death caused by amniotic fluid embolism].

Five cases of amnion fluid embolism are reported. In the first case the cause of the death was the obstruction of the lung-vessels. In the lung tissue calcium embolia could also been detected. In the second case embolization started--at unruptured amnionsac--with ecclampsia-like convulsions, later it was followed by coagulopathia. In the third case amnion fluid embolism was complicated by coagulopathia. In the fourth case in addition to amnion fluid embolism endometritis purulenta complicated by endotoxinaemia and coagulopathia were also present. In all four cases rupture of the uterus was revealed. In the fifth case amnion fluid embolism developed without the rupture of the uterus. At the autopsy of cases of maternal death the possibility of amnion fluid embolism should always be considered. Although macroscopic changes seen at amnion fluid embolism are not pathognomic, when clinical and pathological symptoms of haemorrhagic diathesis are present, there always arises the suspicion of amnion fluid embolism. Since lungs are relatively resistant to putrefaction amnion fluid embolism in optimal cases can be diagnosed histologically even in exhumated lung specimen. Reliable diagnosis of amnion fluid embolism in cases of sudden maternal death gives possibility to exclude medical negligence.

Adult↗
PubMedDate not supplied

[Suicide with an unusual shotgun].

The authors describe a special case of suicide, committed by a self-constructed nailgun. The inshot-wound, localized in the mouth, primarily remained undiagnosed. The patient survived two weeks and died of pulmonary embolism.

Aged↗