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Biomedical subjects

V F Holmes

Publications and source records attributed to V F Holmes.

23 records · Page 2Linked to original sources
PubMed1987

Decreased extrapyramidal symptoms with intravenous haloperidol.

In a preliminary, prospective study, the intensity of extrapyramidal symptoms was rated in four patients receiving intravenous haloperidol and six patients receiving oral haloperidol. The raters were blind to the route of administration. In this pilot study, the first systematic evaluation of intravenous haloperidol and extrapyramidal symptoms, the patients receiving intravenous haloperidol experienced significantly (p less than .01) less intense extrapyramidal symptoms than did the patients receiving oral haloperidol. The literature on intravenous haloperidol is briefly reviewed, and possible explanations of the lower intensity of extrapyramidal symptoms with intravenous haloperidol in the patients studied are discussed.

Administration, Oral↗
PubMed1987

Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin.

Effective analgesia is a crucial factor in promoting quality of life for cancer patients. While undergoing treatment with the minor tranquilizer alprazolam for a coincidental psychiatric disturbance, 39 patients with malignancies and an associated causalgic pain syndrome had a marked analgesic response. Diagnostic and treatment guidelines for organic pain syndromes are reviewed, as are indications for the use of anticonvulsants and benzodiazepines as analgesic adjuvants. The results of this study suggest that the use of benzodiazepines for patients with this refractory pain syndrome should be evaluated further.

Adjustment Disorders↗
PubMed1987

Respiratory dyskinesia due to antiemetic therapy in a cancer patient.

Cancer patients commonly receive neuroleptics as antiemetics to relieve nausea and vomiting induced by chemotherapeutic agents. Respiratory dyskinesia, an infrequent, acute, neuroleptic-induced, dystonic reaction, is a potentially life-threatening entity that responds promptly to anticholinergic medication.

Adult↗
PubMedDate not supplied

HIV public policy and psychiatry. An examination of ethical issues and professional guidelines.

The authors examine the interfaces among public policy, legal issues, ethical issues, and physician responsibility for the human immunodeficiency virus (HIV)-infected psychiatric patient within the realms of civil liberties and public health. Current professional guidelines on caring for HIV-infected psychiatric patients are discussed, including discussion of psychotherapy and the potential for behavioral change. The impact of the Tarasoff decision on confidentiality is reviewed, including discussion of whether a precedent was set mandating that a psychiatrist warn identifiable third persons at risk of becoming infected by his or her patient. The management of HIV-infected psychiatric inpatients who continue to put other patients at risk and the impact of HIV carriers on ward milieu are also addressed, as are difficulties encountered with the chronically mentally ill.

Behavior Therapy↗