Search PubMed⌕ Search

Biomedical subjects

V E Zaĭchik

Publications and source records attributed to V E Zaĭchik.

At least 19 recordsLinked to original sources
PubMed1989

[X-ray fluorescent determination of iron, copper, zinc, bromine and rubidium in biopsies of the gastric mucosa].

A method of a combined use of fiber gastroscopy and x-ray fluorescent analysis was elaborated for a study of the chemical composition of the gastric mucosa. Fr, Cu, Zn, Br, and Rb concentrations were determined in gastric mucosa biopsy specimens obtained during fiber gastroscopy, using x-ray fluorescent analysis. The concentrations of trace elements in the gastric mucosa were determined in 13 healthy persons, in 23 patients with chronic mucosal atrophy, in 15--with gastric ulcer, and in 16--with polyps. Besides, the content of trace elements was determined in the tumorous tissue of 66 gastric cancer patients. The results of the investigation revealed a statistically significant rise of mean Fr concentrations on the ulcer edge, in polyps and tumorous tissue as compared to the unchanged mucosa. Polypous tissue differed from the normal gastric mucosa by a low level of Cu, the difference being statistically significant. A tendency to a decrease in Zn content as compared to the unchanged mucosa was noted in the edge of ulcerative defects. The method can be effectively used for intravital studies on Fr, Cu, Zn, Br, and Rb levels in the G. I. tract mucosa.

Biopsy↗
PubMed1983

[Trace elements of bone tumors].

Due to activation analysis involving the use of neutrons from a nuclear reactor, the concentrations of 11 trace elements: scandium, iron, cobalt, mercury, rubidium, selenium, silver, antimony, chrome, zinc and terbium in intact bone and skeletal tumors were measured. 76 specimens of bioptates and resected material of operations for bone tumors and 10 specimens of normal bone tissue obtained in autopsies of cases of sudden death were examined. The concentrations of trace elements and their dispersion patterns in tumor tissue were found to be significantly higher than those in normal bone tissue. Also, the concentrations of some trace elements in tumor differed significantly from those in normal tissue; moreover, they were found to depend on the type and histogenesis of the neoplasm.

Adolescent↗
PubMed1982

[Intrathyroid iodine in the diagnosis of thyroid cancer].

The stable intrathyroid iodine concentrations characteristic of nodular goiter, thyroid adenoma and cancer were determined by means of neutron activation analysis of resected material, Mean iodine levels in the destruction focus in cancer, adenoma and nodular goiter were 32 +/- 5, 174 +/- 38 and 344 +/- 43, respectively. while 960 +/- 91, 527+/-138 and 639+/-66 micrograms of iodine per 1g of wet weight were found in the surrounding apparently intact tissues of thyroid parenchyma. The importance of the difference between the absolute value of iodine concentration in the destruction focus and that in intact tissue for differential diagnosis of thyroid cancer is discussed.

Adenoma↗
PubMed1981

[Histological structure of the prostate and its zinc content at various ages].

As it has been demonstrated by a morphological investigation of the prostate from 85 corpses of various ages, each age period defined has certain specific objective morphometric indices, histological peculiar features of epithelium and changes in zinc content. The prostatic epithelium is the most monomorphous and the least active in the prepubertal group. In persons 14-40 years of age, the epithelium is characterized by morpho-functional features of high activity with preservation of its histological peculiarities. This corresponds to zinc content within the limits 48.10+/-9.10-64.10+/- +/-6.10 mg/kg in dry tissue of the gland. The most outstanding feature of the prostatic epithelium during transitional period of age is polymorphism of its structure, which corresponds to the greatest zinc content (115.10 +/- 13.10 mg/kg). In elderly and old persons this index is somewhat decreasing.

Adolescent↗
PubMed1978

[Bone tumor macroelements].

Neutron-activation method was employed to determine the concentration of magnium, sodium, chlorine, phosphorus and calcium in different bone tumors. In relation to normal skeletal tissue in tumor tissues higher concentrations of chlorine and sodium but lower concentrations of calcium and phosphorus were found. The greatest changes in the macromolecular content were noted in sarcoma tissues. Bone tumors differ reliably one from the other by concentrations or ratios of macroelements concentrations, this fact may be used for the differential diagnosis.

Adolescent↗
PubMed1975

[The functional state of the thyroid gland following partial pancreatectomy].

In Wistar rats a study was made of a functional condition of the thyroid gland 1, 6 and 24 hours after partial pancreatectomy. The following signs-served as criteria of a functional condition of the gland: the amount of neutrone-activated iodine in iron, iodine-absorptive capacity of the gland by I131, the amount of protein-bound stable and radioactive iodine in the blood, a morphological condition of the gland structures. It was demonstrated that, despite the initial intensification of the process of synthesis and secretion in the thyroid gland, its secretory activity fell by the end of the experiment. This reduction is regarded as an adaptive response to partial insulin deficiency.

Animals↗