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Biomedical subjects

V E Vaskovsky

Publications and source records attributed to V E Vaskovsky.

18 recordsLinked to original sources

Sea urchins--a new model for PAF research in embryology.

This study reports on the effect of PAF on sperm motility, fertilization and early embryo development in the sea urchin Strongylocentrotus intermedius. PAF proved to be the amplifier of sperm motility and fertilizing capability at 10(-8)-10(-9) M and was toxic at higher concentrations. BN 52201 did not counteract the PAF action. The advantages of using sea urchins for PAF research in embryology are discussed.

Animals↗

The effect of long-chain N-acylethanolamines on some membrane-associated functions of neuroblastoma C1300 N18 cells.

As reported earlier (Gulaya, N.M., Vaskovsky, V.E., Vystosky, M.V., Volkov, G.L., Govseeva, N.N. and Artemenko, I.P. (1988) Ukr. Biochim. J. 60, 58-63), N-acylphosphatidylethanolamines (NAPE) and products of their catabolism, N-acylethanolamines (NAE), are present in the lipids of neuroblastoma C1300 N18 undifferentiated cells. The present paper describes the distribution of NAE added to culture medium of differentiated cells and its effect on the fast sodium channels and some other membrane characteristics. It is shown that NAE inhibits the destroying action of veratridine on membranes.

Biological Transport↗

A universal reagent for phospholipid analysis.

A simple procedure for preparing a stable stock reagent an working reagents for the detection and determination of phospholipids is proposed, and a simple, rapid and accurate thin-layer chromatographic technique is suggested. The results obtained for egg yolk phospholipids are presented as an example.

Chromatography, Thin Layer↗