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Biomedical subjects

V Dangubić

Publications and source records attributed to V Dangubić.

At least 19 recordsLinked to original sources
PubMed1982

[Late detection of bronchogenic carcinoma].

The retrospective analysis of 1781 patients with bronchogenous carcinoma treated at the Institute of Pulmonary Diseases of the Military Medical Academy within the period 1971-1980 is presented. In 86% cases the disease was discovered according to symptoms because of which the patients had consulted physicians. The time between the onset and the detection of the disease was more than 3 months in the majority of patients and more than 6 months in one third of the patients. In the largest number of patients the disease was detected late when chances for successful intervention were diminished. Only in one third of the patients the disease was localized. Aiming to early detection of bronchogenous carcinoma it is essential to have good knowledge of symptoms both by patients and primary care physicians.

Adult↗
PubMedDate not supplied

[Alveolitis in patients with sarcoidosis].

In 20 patients with pulmonary sarcoidosis bronchoalveolar lavage (BAL) was performed. The cellular content was analysed and lymphocyte subpopulation was determined using monoclonal antibodies. The patients with more than 28% of BAL T lymphocytes are classified as patients with high intensity alveolitis (n = 8) and those with less than 28% of T lymphocytes as low intensity alveolitis (n = 12). Of the total number of BAL T lymphocytes in high intensity alveolitis CD 3+ T cells were 88.8 +/- 8.4% and in low intensity alveolitis 68.2 +/- 13.8% (p < 0.001). In high intensity alveolitis the number of CD 4+ T cells was increased and the number of CD 8+ T cells was decreased which caused the increased index CD 4:CD 8; 9.8 +/- 8.7. In low intensity alveolitis this ratio was 2.2 +/- 1.2. Effects of smoking were also analysed. In smokers the total number of BAL cells was higher 184.0 +/- 47.2 x 10(4) ml of BAL, and in nonsmokers 101.3 +/- 65.1 x 10(4) ml of BAL (p < 0.001). Smoking has no effects on the characteristics of the cellular elements and subpopulation of BAL lymphocytes in patients with sarcoidosis. In 7 patients T lymphocyte subpopulation in the peripheral blood were determined too. Patients with high intensity alveolitis had the increased index CD 4:CD 8 in the peripheral blood compared with low intensity alveolitis.

Adult↗