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Biomedical subjects

V Danel

Publications and source records attributed to V Danel.

46 records · Page 3Linked to original sources
PubMed1980

[Anaesthesia by administration at a constant rate of fentanyl and methohexitone (300 patients). Clinical study (author's transl)].

Two techniques are described, using different concentrations of fentanyl. The first one uses 0,5 mg of fentanyl and 500 mg of methohexitone in 500 ml of a dextrose or saline solution. The second one uses 1 mg of fentanyl and 500 mg of methohexitone in the same 500 ml solution. The whole study took place in bone surgery, with well-prepared and non-stressed patients. The induction and maintenance doses are discussed. The authors emphasize the simplicity of this method; they discuss the advantages and the disadvantages of this easy method of anesthesia in bone surgery, and advise against its use in non-prepared patients.

Aging↗
PubMed1980

[New landmarks for the subclavian approach of the brachial plexus. (With 44 clinical cases) (author's transl)].

The authors first recall the well-known techniques described by Kuhlenkampf, Winnie and others. They emphasize the sometimes difficult location of the subclavian artery, the fear of pneumothorax, especially for students learning this anesthesia method. Authors propose the use of new landmarks for brachial plexus anesthesia. These are the external jugular vein, sterno-cleido-mastoid muscle, and clavicular insertion of trapezius muscle. 44 cases of anesthesia using this method follows the description of the landmarks. The authors emphasize their low failure rate.

Brachial Plexus↗
PubMedDate not supplied

Chronic trichloroethylene intoxication: a new approach by trigeminal-evoked potentials?

Trigeminal nerve impairment is frequently seen in chronic trichlorethylene intoxication (TRI). A total of 104 occupationally exposed subjects were selected for study because they were employed at a highly exposed workplace. They were studied by clinical examination and by trigeminal somatosensory evoked potentials (TSEP). Normal values for TSEP were obtained from the study of 52 healthy nonexposed subjects. Facial hypoesthesia, when present, was global and predominant in the mandibular and maxillary nerve areas, associated or not with absent reflexes. A disturbed TSEP was found in 40 subjects which was predictable from their clinical symptoms. Correlation with exposure parameters (duration of exposure, trichlorethanol, and trichloracetic acid urinary rates) was mainly observed in subjects presenting both clinical and electrical alterations. Electrical alterations alone were less predictive. An abnormal TSEP may thus provide objective determination of risk assessment in the absence of clinical signs.

Adult↗
PubMedDate not supplied

[Biomarkers for toxicity and metabolic abnormalities of the main severe poisonings. Clinical and toxicologic symptoms. Conservative determination].

The members of the joint group "Toxicology and Clinical Biology" of the French Society of Clinical Biology (SFBC), the French Society of Analytical Toxicology (SFTA), and the Society of Clinical Toxicology (STC), suggest guidelines to meet the requirements of clinical biologists who are not specialized in toxicology. Based on good laboratory practice they propose a number of guidelines. Three synthetic tables have been established. They are not only toxicity biomarkers and metabolic disorders associated with the main severe intoxications, but also clinical signs that are observed during these intoxications, finally biological sampling as a precautionary measure. The table also takes into account approximately fifty xenobiotics: main clinical signs emergency, identification or quantification of the suspected product, useful biological markers, therapeutic, quantitations necessary to take into consideration patient care, and poison antidotes, are described. Recommendations regarding medical and forensic techniques are also proposed by the group. It is also necessary to collect and store biological samples when the individual patients are in charge. These samples will be analyzed or not depending on the individual case history.

Biomarkers↗
PubMedDate not supplied

[Digitalis poisoning in children. Treatment with anti-digoxin Fab antibody fragments. Apropos of a case and a discussion of therapeutic indications].

We report one case of Digoxin intoxication in a child treated with Fab Fragments of Digoxin-Specific antibodies (Fabad), although there was no evidence of early life threatening complications. The efficacy of this treatment, which prevents further complications as well as its safety, represent strong arguments to treat children at the early stage of the intoxication in order to avoid temporary cardiac pacing.

Antibodies↗