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Biomedical subjects

V D Trush

Publications and source records attributed to V D Trush.

At least 19 recordsLinked to original sources
PubMed1984

Experimental data on the nature of postresuscitation alpha frequency activity.

Synchronized activity of alpha frequency recorded from a number of dog brain formations in the initial stages of postischaemic (postresuscitation) restoration was studied. Using the methods of destruction and elimination it was shown that the amygdaloid nuclei were the main source of such activity. Analysis of the general and particular coherence functions at the frequencies of alpha-like activity has shown that subcortical formations (thalamus, nucleus caudatus) become secondarily active sources of the generation of the bursts and of their generalization in the brain. Investigations and available literature lay the basis for the hypothesis that the activity observed in experiments and the activity described during postresuscitation alpha-pattern coma in humans have similar mechanisms of development and are, probably, identical.

Amygdala↗
PubMed1981

[Role of certain brain structures in the generation and spread of alpha-like activity in dogs peculiar to the early stages of the postresuscitation period].

The role played by the amygdaloid nucleus, caudate nucleus, thalamus and brain cortex in propagation throughout the brain of generalized limbic alpha-like activity recorded on the EEG in the early postresuscitation period was studied in experiments on dogs resuscitated after a 13-15-minute circulatory arrest. Destruction or pharmacological inhibition of both amygdaloid nuclei resulted in disappearance of alpha-like activity from all the test structures. Coherent analysis showed that the caudate nucleus and thalamus, in particular, take an active part in propagation of alpha-like waves of biopotentials from the amygdaloid nucleus to other brain structures.

Amygdala↗
PubMed1977

[Excitability of the senso-motor cortex and red nucleus of rabbits with different levels of cortical potential spatial synchronization].

The motor reaction of the rabbit to the threshold electrical stimulation of the sensomotor cortex and red nucleus was studied to determine excitability of these structures. Under conditions of the computer-controlled experiment the excitability of the two structures was compardd for situations characterized by different levels of cortical potential correlation. An increase in the spatial synchronization of the cortical potentials is shown to be accompanied by intensification in excitability of the sensomotor cortex and red nucleus. This intensification seems to be one of possible neurophysiological mechanisms of the probability increase for the effector reaction to sensory stimuli when the cortical spatial synchronization rises.

Animals↗
PubMed1976

[Spectral-correlation analysis of the bioelectrical activity of rabbit brain structures during electrosleep].

Changes of electric activity of the rabbit cortical and subcortical structures were studied by means of spectrum-correlation analysis during sleep caused by low-frequency stimulation of the supraoptic hypothalamic nucleus. The electrosleep affected the similarity of the electric events in neocortex and subcortical structures. The disturbance of the spatial synchronization is supposed to be due to the activity of nonsynchronized autonomous bioelectric pace-makers in different brain structures.

Animals↗
PubMed1975

[Space-time parameters of the biopotentials in rabbit brain structures during natural sleep].

Different stages of natural slow-wave sleep were studied in rabbits with the aid of spectro-correlation analysis using the direct input of data to the computer. The main findings regularly observed after sleep were as follows: the decrease of synchronization between biopotentials led from different brain structures, the absence of uniform Q-band rhythms and the reduced coherence of this band, phase discrepancy between low-frequency components. Thereupon the state of inhibition is concluded to be characterized by the spatio-temporal discrepancy in the brain electric activity.

Animals↗
PubMed1973

Power spectra of cortical electric activity in the rabbit in relation to conditioned reflexes.

In chronic experiments on rabbits spectral and correlation characteristics of cerebral cortical potentials were computed to study the elaboration of a conditioned defense reflex. was found that the frequency spectra of the EEG are subject to consistent changes: a narrow-band frequency constantly developing in the theta range. During exposure to a positive conditioned stimulus, the maximum of this frequency increased relative to the pre-stimulus period and a maximal coherence of electrical processes was observed in a narrow theta range between the electrical processes of the cortical analyzers to which the conditional and unconditional stimuli were addressed. Different relationship was noted in the theta range during presentation of a differential or extinguishing stimuli: it became slightly slower than in the pre-stimulus period, and the coherence of the theta rhythms was less than maximal, remaining high at the other frequencies. It was concluded that the presence of highly coherent electrical processes in the theta range is important for the formation of conditioned reflex in the rabbit cerebral cortex. The processes of internal inhibition are characterized electrographically by disagreement of electrical processes in the theta range in respect to phase or frequency.

Animals↗