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Biomedical subjects

V Colletti

Publications and source records attributed to V Colletti.

8 recordsLinked to original sources
PubMed1991

Reduced active protection to the cochlea during physical exercise.

The present investigation was designed to evaluate whether dynamic physical exercise is able to modify stapedius reflex (SR) activity and, as a consequence, to influence the amount of temporary threshold shift (TTS). Experimental subjects were 10 normal-hearing male volunteers, aged 27-34 years (mean 30.8). SR parameters in the time-domain were assessed before, during and after submaximal exercise test, performed for 10 min on an ergometer cycle at 50% of maximum work capacity. The same parameters were also investigated in the absence of exercise, at time-matched intervals. In addition, the combined effect of noise and exercise was studied. The outcome of the investigation indicates that dynamic physical exercise depresses the SR and potentiates noise-induced TTS. The mechanisms underlying the present findings are discussed.

Adult↗
PubMed1991

Surgery vs. natural course of chronic otitis media. Long-term hearing evaluation.

The present paper investigates the hearing function in chronic otitis media vs. tympanoplasty in 41 patients with bilateral chronic otitis media, operated on unilaterally. The auditory evaluation was performed immediately before surgery and at a follow-up time varying from 1 to 14 years (mean = 5 years). Results were expressed in terms of relative gain (in respect to preoperative hearing levels) and total gain (in comparison with the contralateral ear). A progressive reduction of the hearing threshold as a function of time was observed both in non-operated and operated ears. The comparison of the threshold shifts between the two ears indicated that the long-term functional results of tympanoplasty can be considered quite satisfactory.

Adult↗
PubMed1991

Effect of sodium fluoride on early stages of otosclerosis.

The present investigation evaluates the effectiveness of NaF treatment in modifying the natural course of subclinical otosclerosis, as monitored by the stapedius reflex. The study was carried out on 128 relatives of patients suffering from surgically confirmed footplate otosclerosis. The diagnosis of subclinical otosclerosis was made on the basis of presence of the on-off effect. One group of subjects was treated with NaF in doses ranging from 6 to 16 mg according to age. The treatment lasted 2 years. A second group served as a control. Changes in stapedius reflex morphology were evaluated at 1, 2, and 5 years from the onset of treatment. The investigation demonstrated that NaF has a stabilizing effect on early otosclerosis. This drug, in fact, arrests the disease process in more than 60 percent of ears at the 2-year follow-up and in more than 50 percent at 5 years. A program of secondary prevention of otosclerosis by NaF is suggested.

Adolescent↗
PubMed1976

Tympanomety from 200 to 2000 Hz probe tone.

Previous investigations have shown that the probe tone frequency is the main factor in determing the shape of the tympanogram. These had, however, been limited up to 800 Hz. In the present paper, a multifrequency investigation (from 200 to 2000 Hz) has been performed on 72 ears with different pathophysiological conditions of the middle ear. From the analysis of the result some new critical aspects of tympanometry emerge. The multifrequency tympanometric investigation proves to be, according to our experience, a far more sensitive method for checking small changes in the transmission characteristics of the tympano-ossicular system than the monofrequency traditional analysis. In this connection, the technique seems to furnish a simple and reliable method for discriminating between stiffness versus mass-controlled systems.

Audiometry↗
PubMedDate not supplied

Methodologic observations on tympanometry with regard to the probe tone frequency.

Changes in the tympanogram shape in the frequency range from 200 to 2000 Hz have been investigated. The tympanogram undergoes, as the probe tone frequency rises, characteristic morphologic modifications which are consistently observed both in normals and in some middle ear disorders. The only exception to this regular behavior is the pathological picture in which the structure or the dynamic of the tympano-ossicular system is remarkably anomalous (cholesteatoma and otitis media) where there are flat tympanograms. It is suggested that the frequency interval at which one of the characteristic tympanometric configurations appears in the element capable of furnishing a diagnostic tool for differentiating pathophysiologic conditions of the middle ear.

Air Pressure↗
PubMedDate not supplied

Stapedius reflex abnormalities in multiple sclerosis.

Thirteen patients suffering from multiple sclerosis were analyzed by a Madsen ZO 70 electroacoustic bridge connected to an electronystagmograph through an impedance adaptor. Threshold, amplitude, decay and difference limen of intensity (DLI) of the stapedius reflex were examined for the frequencies 500, 1 000, 2 000 and 4 000 Hz. The difference between standard audiometric results and stapedius reflex data stresses the value of reflex measurements in assessing brain stem pathology.

Acoustic Stimulation↗
PubMedDate not supplied

Multifrequency tympanometry.

The tympanogram shape has been investigated in 290 patients as a function of probe tone frequency (from 200 to 2000 Hz). As the frequency of the probe tone rises, the tympanogram undergoes characteristic modifications which have been grouped, according to their morphologic similarities, in three classes: V, W and inverted-V shape. These three tympanometric configurations are consistently observed both in normals and in some patients with middle ear disorders. Exceptions to this regular behaviour are the pathological pictures of the middle ear in which the structure or the dynamics of the tympano-ossicular system are significantly altered (massive tympanosclerosis, glue ear and cholesteatoma). The frequency interval at which the characteristic tympanometric configurations appear is the most important factor for differentiating pathophysiologic conditions of the middle ear.

Audiometry↗