Biomedical subjects
V Campos
Publications and source records attributed to V Campos.
Dental treatment of hydrotic hereditary ectodermal dysplasia.
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New peroxides and their antimicrobial activity.
Antimicrobial activity of hydroperoxides and cyclic peroxides has been studied. 2,4-Dihydroperoxy-2,4-dimethylpentane (1) and 2,5-dihydroperoxy-2,5-dimethylhexane (2) were active against microorganism, but 1 showed a large specially against C. albicans, M. luteus and B. subtilis with a MIC value of 31.5 mcg/ml.
Tolerance to pirprofen and preliminary efficacy trial in rheumatoid arthritis.
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[Analysis of penicillin-resistant staphylococcus developed in a continuous culture].
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[123 I-MIBG myocardial sympathetic innervation scintigraphy and Parkinson's disease. Preliminary results].
OBJECTIVES: Cardiac sympathetic function in patients with Parkinson's disease (PD) is significantly impaired. Cardiac scintigraphy with 123I-metaiodobenzylguanidine (123I-MIBG) is used to assess cardiac sympathetic function. METHODS: A total of 29 consecutive patients with PD and 10 control subjects without neurological disease were studied. Myocardial imaging with 123I-MIBG was performed to evaluate cardiac sympathetic function. Early and delayed images of the anterior view were obtained at 15 min. and 4 h. after injection of 123I-MIBG, respectively. 123I-MIBG uptake was quantified qualitatively and semiquantitatively by calculating a heart-to-mediastinum (H/M) ratio. RESULTS: The heart/mediastinum ratio was markedly reduced in patients with PD (I to IV on the Hoehn and Yahr scale) when compared to the control subjects (p < 0.05). This finding was independent of the length and severity of the disease or the pharmacological treatment of the patients. None of the control subjects showed decrease in myocardial 123I-MIBG uptake. CONCLUSIONS: Our findings indicate that a decrease in myocardial accumulation of 123I-MIBG was observed in the early stages of PD. This suggests that the measurement of 123I-MIBG may help the early diagnosis of PD, and can be used to detect cardiac autonomic dysfunction, especially in patients without typical signs and symptoms.
Compound odontoma--diagnosis and treatment: three case reports.
Odontomas are the most common type of odontogenic tumors and generally they are asymptomatic. This paper describes three cases of compound odontomas diagnosed in children due to dislodgement or over-retention of primary anterior teeth and/or swelling of the cortical bone. In all cases, the surgical excision of the lesions was performed and, in one case, orthodontic treatment was adopted in order to move an impacted permanent tooth to its normal position. The results achieved indicate that the early diagnosis of odontomas allows the adoption of a less complex and expensive treatment and ensures better prognosis.
Effects of calcium entry blockers on KCl- and 5-hydroxytryptamine-induced contractions of human umbilical arteries.
The effects of Ca2+ removal and of the calcium entry blockers, nicardipine and nifedipine, on contractions of isolated human umbilical arteries, elicited with KCl and 5-hydroxytryptamine, were investigated. Withdrawal of Ca2+ caused inhibition of both KCl and 5-hydroxytryptamine responses, but the maximum effect of KCl in Ca2(+)-free medium was recuperated by increasing the KCl concentration. The maximum effect of 5-hydroxytryptamine, however, was recuperated only when Ca2+ was restored to the medium. Consistently with an inhibition in Ca2(+)-free medium, calcium entry blockers produced a concentration-dependent relaxation of human umbilical artery strips precontracted with KCl and 5-hydroxytryptamine, and inhibited the concentration-dependent contraction elicited by these stimuli. Our results indicate that contractile responses of the human umbilical arteries are dependent on extracellular Ca2+ for both KCl and 5-hydroxytryptamine. Although Ca2+ entry was sensitive to both nicardipine and nifedipine, the differences between the effects of these dihydropyridines with the two experimental approaches we used were not always conclusive.
[Variations in the beta-lactame resistance of Staphylococcus and Pseudomonas cultivated in a chemostat].
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