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Biomedical subjects

V C Cousins

Publications and source records attributed to V C Cousins.

11 recordsLinked to original sources
PubMed2001

Improving public mental health services for trauma victims in South Carolina.

Studies have shown that trauma and posttraumatic stress disorder are highly prevalent among persons with serious mental illness who are treated in state-funded mental health systems. Nevertheless, there is strong evidence that many of these persons receive inadequate mental health services. South Carolina recently became one of at least 15 states whose departments of mental health have initiated efforts to better address these needs. The goals of this initiative are to sensitize stakeholders, influence policies, educate and train clinicians, and increase knowledge by supporting a strong empirical research platform. Current progress and future directions are described in this article.

Community Mental Health Services↗
PubMed1994

Absence of toxicity in patients with malignant otitis externa following long-term treatment with high dosage tobramycin.

An in-vitro model of aminoglycoside dosing was used to demonstrate that the bactericidal activity of tobramycin against Pseudomonas aeruginosa is directly related to the peak concentration of the drug. In addition, six patients who were being treated for malignant otitis externa with long-term, high dosage tobramycin were monitored for oto- and nephro-toxicity; the only adverse effects were transient increases in the serum creatinine concentration in two patients.

Aged↗
PubMed1991

Sinusoidal harmonic acceleration testing in normal humans.

Forty-one normal humans were tested with sinusoidal harmonic acceleration. Phase lag at 0.01, 0.02, and 0.04 Hz was the most stable parameter, with less test-retest variability than gain and asymmetry. There was no significant difference between men and women for phase lag, gain, or asymmetry at any of the five testing frequencies. Gain decreased as age increased. Age had no effect on phase lag at most test frequencies or on asymmetry at any frequency.

Acceleration↗
PubMed1988

Congenital ossicular abnormalities: a review of 68 cases.

Sixty-eight cases of congenital conductive hearing loss due to ossicular abnormalities were reviewed. The clinical and surgical details of each case were documented, and a classification was drawn up on the basis of the abnormalities encountered. Sixty-six percent of the cases were documented as middle ear anomalies in the absence of any other evidence of congenital disease. Improved hearing was obtained in 47% of those cases where corrective surgery was undertaken. Treatment and results are reviewed. The pattern of ossicular abnormality encountered in this series suggests a variable origin of the incus, either from first branchial arch alone or from both first and second branchial arches.

Abnormalities, Multiple↗
PubMed1987

Light and electronmicroscopic studies on Polycel ossicular replacement prostheses.

Recently, a new form of porous high density polyethylene (Polycel) has been promoted for use in ossicular chain reconstruction. However, we have found no reports of investigation of the fate of this material used for this purpose in either animals or man. This study was undertaken to look at the tissue tolerance and fate of Polycel in the middle ear of gerbils before its extensive use in humans. We present the light and transmission electromicroscopic findings from these prostheses, removed from the middle ear between 1 and 5 months post-implantation. The results are similar to those found with Plastipore, showing a strong foreign body reaction and the likelihood of phagocytic consumption. As with the other porous plastics, we have reservations about the use of Polycel for ossicular reconstruction.

Animals↗
PubMed1987

Craniofacial resection of extensive benign lesions of the anterior skull base.

The craniofacial resection operation was developed for the treatment of advanced nasal, paranasal and orbital malignancies. It has been refined in recent years, giving increased cure rates and better palliation when cure is not possible. When used to treat extensive benign lesions involving the anterior skull base, this procedure allows more complete and safer resection with better access for repair and avoidance of major complications of brain damage, cerebrospinal fluid leak and haemorrhage. Presented here is a technique for craniofacial resection. The study demonstrates its effectiveness and low morbidity in treating 10 patients with extensive benign disease.

Adolescent↗
PubMed1986

Problems in clinical assessment of palatal tumours.

This paper reviews the classification of tumours affecting the palate. The embryology and anatomy of the palate are outlined in relation to the TNM classification of the International Union Against Cancer (UICC) and American Joint Committee on Cancer (AJC) for the oral cavity and oropharynx. A series of 80 palatal tumours is reviewed to assess the adequacy of the classification schemes in providing accurate data for tumour treatment comparison. Both schemes rely on relatively crude assessment of total tumour extent and neither provides enough detail to allow valid comparisons.

Female↗