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Biomedical subjects

V Bowen

Publications and source records attributed to V Bowen.

28 records · Page 2Linked to original sources

Cerclage wiring of metacarpal fractures.

Preventing the deformities of rotation and shortening is essential in the treatment of metacarpal fractures. Maintenance of accurate reduction is often difficult to achieve by cast immobilization or by the more sophisticated techniques that use plates and screws. During a four-year period, 92 of 290 metacarpal fractures were treated by open reduction and internal fixation. Of these, 21 were oblique and spiral fractures that were treated by cerclage wiring. The operation is performed with two to three lengths of No. 24 prestretched stainless steel wire that is tightened around the metacarpal shaft following fracture reduction. Mobilization of the hand is begun ten days following surgery, and full, unlimited use is permitted after six weeks. All 21 metacarpal fractures were followed up until the patient was ready to return to work, which occurred an average of seven weeks after surgery. Seventeen patients had no restriction of range of motion, with normal anatomic restoration of the metacarpal. Three patients lost 15 degrees of total active finger motion, and one had an extension lag of 10 degrees at the metacarpophalangeal joint.

Adolescent↗

Flexor tenosynovitis caused by Coccidioides immitis.

Coccidioidomycosis is a rare disease and dissemination of the pulmonary infection occurs in less than 0.1% of cases. A case report of coccidioidal tenosynovitis in association with immunosuppressive chemotherapy is described. Recommended management includes both intravenous amphotericin B and surgical synovectomy.

Coccidioidomycosis↗

Lumbar spinal stenosis: a review article.

(1) In discussing the types of lumbar spinal stenosis, emphasis has been placed on the developmental form. (2) The importance of nerve entrapment in the lateral recess has been stressed. (3) An attempt has been made to demonstrate the relationship of developmental stenosis to other lesions affecting the lumbar spine. (4) Our knowledge of the development of the lumbar spine and its patho-anatomy in children is limited. (5) Attention to minor trauma and to preventive measures during childhood will do much to prevent stenosis in later years.

Adolescent↗

Insulin release from the perfused rat pancreas. Mode of action of tolbutamide.

Dextran-linked tolbutamide causes first-phase insulin release when perfused through the isolated rat pancreas. The linked sulphonylurea is also able to stimulate the membranal adenylate cyclase present in mouse islets. These facts make it highly likely that sulphonylureas exert their pharmacological action by interaction with the plasma membrane. Their action may be mediated via the adenylate cyclase enzyme.

Adenosine Triphosphate↗

The free vascularised iliac crest tissue transfer: donor site complications associated with eighty-two cases.

Seventy-eight patients who had undergone a total of 82 free vascularised iliac crest tissue transfers were reviewed to determine the incidence of donor site complications. The most frequent problems encountered were early postoperative pain and long term sensory changes. Major complications such as femoral neuropathy and incisional hernia formation were encountered infrequently. More serious potential complications are discussed. In general, the functional loss associated with the free vascularised iliac crest tissue transfer was found to be acceptable, but the inclusion of a skin paddle was noted to be associated with a greater incidence of sensory changes, hernia formation and contour abnormalities.

Adolescent↗

Macroscopic and microscopic anatomy of the sacroiliac joint from embryonic life until the eighth decade.

The macroscopic and microscopic anatomy of the sacroiliac joint from embryonic life until the eighth decade is presented to establish a baseline of normal anatomy for this joint. The literature concerning the anatomy of the joint was reviewed and found to be fragmentary and conflicting, particularly concerning the diarthroidial characteristics of the joint. From fetal life onward, the iliac cartilage surface is fibrocartilaginous, while the sacral surface is hyaline cartilage. Degenerative arthrosis of the joint commences at an early age, affecting the iliac cartilage to a greater extent than its sacral counterpart. These early degenerative changes in the sacroiliac joint may very well be a more common cause of low-back pain than previously thought.

Adolescent↗

Transfer of free vascular cutaneous flaps by microvascular anastomosis. Results in six dogs.

Skin defects on the distal extremities of six dogs were reconstructed with free vascular cutaneous transfers by microvascular anastomosis. The donor flaps were based on the superficial cervical artery and vein. In five of the dogs, bone was exposed and skin was lost from half of the circumference of the limb. Two had infected fractures with sequestra and three had acute shearing injuries. The sixth dog had sensory denervation of the left antebrachium and a carpal acral lick granuloma. Before surgery, the patency of potential recipient vessels was confirmed with arteriography in five dogs and an ultrasonic doppler in one dog. Microvascular technique was used to reestablish circulation to the flaps after they were transferred to the recipient site. Total ischemic time of the flaps averaged 100 minutes. All flaps survived. Successful reconstruction of the cutaneous defects was achieved in these six cases.

Anastomosis, Surgical↗

A developmental model for free vascularized bone transfers in the dog.

An autogenous free vascular bone transfer using a segment of ulna along with its periosteum and vascular pedicle was developed. The vascular pedicle, based on the common interosseous artery and vein, emerged where muscular branches from the cranial interosseous artery enter the extensor carpi ulnaris and lateral digital extensor muscles. Four autogenous heterotopic (ulna to tibia) vascular transfers by microvascular anastomosis and two avascular transfers were performed to compare the osteogenic potential and viability of free revascularized grafts with avascular bone grafts. Successful microvascular anastomosis was demonstrated in three of the four vascular transfers by early bone scanning using technetium-labeled polyphosphate. Radiographically, there was more periosteal new bone and callus formation in the successfully revascularized bone transfers than in the failed vascular transfer and the avascular controls. Histologically, viable bone with an intact medullary and periosteal vascular supply was recognized in the grafts successfully revascularized by microvascular anastomosis.

Animals↗